PROFILBARU.COM

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

GalNAc5-diNAcBac-PP-undekaprenol beta-1,3-glukoziltransferaza
GalNAc5-diNAcBac-PP-undekaprenol beta-1,3-glukoziltransferaza
Identifikatori
EC broj	2.4.1.293
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

GalNAc5-diNAcBac-PP-undekaprenol beta-1,3-glukoziltransferaza (EC 2.4.1.293, PglI) je enzim sa sistematskim imenom UDP-alfa-D-glukoza:(GalNAc-alfa-(1->4))4-GalNAc-alfa-(1->3)-diNAcBac-difosfo-tritrans,heptacis-undekaprenol 3-beta-D-glukoziltransferaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

UDP-alfa-D-glukoza + [GalNAc-alfa-(1->4)]4-GalNAc-alfa-(1->3)-diNAcBac-difosfo-tritrans,heptacis-undekaprenol

\rightleftharpoons

UDP +

[GalNAc-alfa-(1->4)]2-[Glc-beta-(1->3)]-[GalNAc-alfa-(1->4)]2-GalNAc-alfa-(1->3)-diNAcBac-difosfo-tritrans,heptacis-undekaprenol

Ovaj enzim je izolovan iz Campylobacter jejuni.

Reference

^ Glover, K.J., Weerapana, E. and Imperiali, B. (2005). „In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation”. Proc. Natl. Acad. Sci. USA. 102: 14255—14259. PMID 16186480.
^ Kelly, J., Jarrell, H., Millar, L., Tessier, L., Fiori, L.M., Lau, P.C., Allan, B. and Szymanski, C.M. (2006). „Biosynthesis of the N-linked glycan in Campylobacter jejuni and addition onto protein through block transfer”. J. Bacteriol. 188: 2427—2434. PMID 16547029.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

GalNAc5-diNAcBac-PP-undecaprenol+beta-1,3-glucosyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Glover, K.J., Weerapana, E. and Imperiali, B. (2005). „In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation”. Proc. Natl. Acad. Sci. USA. 102: 14255—14259. PMID 16186480.

[2] Kelly, J., Jarrell, H., Millar, L., Tessier, L., Fiori, L.M., Lau, P.C., Allan, B. and Szymanski, C.M. (2006). „Biosynthesis of the N-linked glycan in Campylobacter jejuni and addition onto protein through block transfer”. J. Bacteriol. 188: 2427—2434. PMID 16547029.

[1]

[2]