Abieta-7,13-dien-18-al dehidrogenaza

Abieta-7,13-dien-18-al dehidrogenaza
Identifikatori
EC broj	1.2.1.74
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC članci PubMed članci NCBI proteini

Abieta-7,13-dien-18-al dehidrogenaza (EC 1.2.1.74, abietadienalna dehidrogenaza (ambiguous)) je enzim sa sistematskim imenom abieta-7,13-dien-18-al:NAD⁺ oksidoreduktaza.^[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

abieta-7,13-dien-18-al +H₂O + NAD⁺ ${\displaystyle \rightleftharpoons }$ abieta-7,13-dien-18-oat + NADH + H⁺

Abietska kiselina je glavna komponenta smole četinara. Ovaj enzim katalizuje zadnji korak u biosintezi abietske kiselina kod Abies grandis.

Reference

1. Funk, C. & Croteau, R. (1994). „Diterpenoid resin acid biosynthesis in conifers: characterization of two cytochrome P450-dependent monooxygenases and an aldehyde dehydrogenase involved in abietic acid biosynthesis”. Arch. Biochem. Biophys. 308: 258—266. PMID 8311462. 
2. Funk, C., Lewinsohn, E., Vogel, B.S., Steele, C.L. and Croteau, R. (1994). „Regulation of oleoresinosis in grand fir (Abies grandis) (coordinate induction of monoterpene and diterpene cyclases and two cytochrome P450-dependent diterpenoid hydroxylases by stem wounding)”. Plant Physiol. 106: 999—1005. PMID 12232380. CS1 одржавање: Вишеструка имена: списак аутора (веза)

Literatura

• Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
• Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 
• William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605. 

Spoljašnje veze

• Abieta-7,13-dien-18-al+dehydrogenase на US National Library of Medicine Medical Subject Headings (MeSH)