16S rRNK (guanin966-N2)-metiltransferaza

16S rRNK (guanin^966-N^2)-metiltransferaza
Identifikatori
EC broj	2.1.1.171
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC članci PubMed članci NCBI proteini

16S rRNK (guanin⁹⁶⁶-N²)-metiltransferaza (EC 2.1.1.171, yhhF (gen), rsmD (gen), m2G966 metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:16S rRNK (guanin⁹⁶⁶-N²)-metiltransferaza.^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

S-adenozil-L-metionin + guanin⁹⁶⁶ u 16S rRNK ${\displaystyle \rightleftharpoons }$ S-adenozil-L-homocistein + N²-metilguanin⁹⁶⁶ u 16S rRNK

Ovaj enzim efikasno metiliše guanin⁹⁶⁶ u formiranim 30S podjedinicama in vitro.

Reference

1. Lesnyak, D.V., Osipiuk, J., Skarina, T., Sergiev, P.V., Bogdanov, A.A., Edwards, A., Savchenko, A., Joachimiak, A. and Dontsova, O.A. (2007). „Methyltransferase that modifies guanine 966 of the 16 S rRNA: functional identification and tertiary structure”. J. Biol. Chem. 282: 5880—5887. PMID 17189261. CS1 одржавање: Вишеструка имена: списак аутора (веза)

Literatura

• Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
• Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 

Spoljašnje veze

• 16S+rRNA+(guanine966-N2)-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)