UDP-N-acetilglukozamin—dolihil-fosfat N-acetilglukozaminfosfotransferaza

UDP-N-acetilglukozamin—dolihil-fosfat N-acetilglukozaminfosfotransferaza
Identifikatori
EC broj	2.7.8.15
CAS broj	70431-08-2
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

UDP-N-acetilglukozamin—dolihil-fosfat N-acetilglukozaminfosfotransferaza (EC 2.7.8.15, UDP-D-N-acetilglukozamin N-acetilglukozamin 1-fosfatnana transferaza, UDP-GlcNAc:dolihil-fosfat GlcNAc-1-fosfatna transferaza, UDP-N-acetil-D-glukozamin:dolihol fosfat N-acetil-D-glukozamin-1-fosfat transferaza, uridin difosfoacetilglukozamin-dolihil fosfatna acetilglukozamin-1-fosfotransferaza, chitobiozilpirofosforildoliholna sintaza, dolihol fosfat N-acetilglukozamin-1-fosfotransferaza, UDP-acetilglukozamin-dolihol fosfat acetilglukozamin fosfotransferaza, UDP-acetilglukozamin-dolihol fosfat acetilglukozamin-1-fosfotransferaza) je enzim sa sistematskim imenom UDP-N-acetil-D-glukozamin:dolihil-fosfat N-acetil-D-glukozaminfosfotransferaza.^[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

UDP-N-acetil-D-glukozamin + dolihil fosfat ${\displaystyle \rightleftharpoons }$ UMP + N-acetil-D-glukozaminil-difosfodolihol

Reference

1. Sharma, C.B., Lehle, L. and Tanner, W. (1982). „Solubilization and characterization of the initial enzymes of the dolichol pathway from yeast”. Eur. J. Biochem. 126: 319-325. PMID 6215245. 
2. Villemez, C.L. and Carlo, P.L. (1980). „Properties of a soluble polyprenyl phosphate. UDP-D-N-acetylglucosamine N-acetylglucosamine-1-phosphate transferase”. J. Biol. Chem. 255: 8174-8178. PMID 6447695. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH UDP-N-acetylglucosamine---dolichyl-phosphate+N-acetylglucosaminephosphotransferase