TRNK sumportransferaza

TRNK sumportransferaza
Identifikatori
EC broj	2.8.1.4
CAS broj	9055-57-6
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

TRNK sumportransferaza (EC 2.8.1.4, transfer ribonukleatna sumportransferaza, RNK sumportransferaza, ribonukleatna sumportransferaza, transfer RNK sumportransferaza, transfer RNK tiolaza) je enzim sa sistematskim imenom L-cistein:tRNK sumportransferaza.^[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

L-cistein + aktivirana tRNK ${\displaystyle \rightleftharpoons }$ L-serin + tRNK sa tionukleotidom

Ova grupa enzima prenosi sumpor na razne nukleotide u tRNK lancu.

Reference

1. Abrell, J.W., Kaufman, E.E. and Lipsett, M.N. (1971). „The biosynthesis of 4-thiouridylate. Separation and purification of two enzymes in the transfer ribonucleic acid-sulfurtransferase system”. J. Biol. Chem. 246: 294-301. PMID 5541999. 
2. Hayward, R.S. and Weiss, S.B. (1966). „RNA thiolase: the enzymatic transfer of sulfur from cysteine to sRNA in Escherichia coli extracts”. Proc. Natl. Acad. Sci. USA 55: 1161-1168. PMID 5334200. 
3. Lipsett, M.N. and Peterkofsky, A. (1966). „Enzymatic thiolation of E. coli sRNA”. Proc. Natl. Acad. Sci. USA 55: 1169-1174. PMID 5334201. 
4. Wong, T., Weiss, S.B., Eliceiri, G.L. and Bryant, J. (1970). „Ribonucleic acid sulfurtransferase from Bacillus subtilis W168. Sulfuration with β-mercaptopyruvate and properties of the enzyme system”. Biochemistry 9: 2376-2386. PMID 4987417. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH TRNA+sulfurtransferase