Sekundarni alkohol oksidaza

Sekundarni alkohol oksidaza
Identifikatori
EC broj	1.1.3.18
CAS broj	71245-08-4
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Sekundarni alkohol oksidaza (EC 1.1.3.18, polivinil alkohol oksidaza) je enzim sa sistematskim imenom sekundarni-alkohol:kiseonik oksidoreduktaza.^[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

sekundarni alkohol + O₂ ${\displaystyle \rightleftharpoons }$ keton +H₂O₂

Ovaj enzim deluje na sekundarne alkohole sa pet ili više ugljenika, i polivinilne alkohole sa molekulskom masom preko 300 Da. Pseudomonas enzim sadrži jedan atom gvožđa izvan hema po molekulu.

Reference

1. Morita, M., Hamada, N., Sakai, K. and Watanabe, Y. (1979). „Purification and properties of secondary alcohol oxidase from a strain of Pseudomonas”. Agric. Biol. Chem. 43: 1225-1235. 
2. Sakai, K., Hamada, N. and Watanabe, Y. (1983). „Separation of secondary alcohol oxidase and oxidized poly(vinyl alcohol) hydrolase by hydrophobic and dye-ligand chromatographies”. Agric. Biol. Chem. 47: 153-155. 
3. Suzuki, T. (1976). „Purification and some properties of polyvinyl alcohol-degrading enzyme produced by Pseudomonas O-3”. Agric. Biol. Chem. 40: 497-504. 
4. Suzuki, T. (1977). „Oxidation of secondary alcohols by polyvinyl alcohol-degrading enzyme produced by Pseudomonas O-3”. Agric. Biol. Chem. 42: 1187-1194. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH Secondary-alcohol+oxidase