Nukleozid fosfotransferaza

Nukleozid fosfotransferaza
Identifikatori
EC broj	2.7.1.77
CAS broj	9055-37-2
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Nukleozid fosfotransferaza (EC 2.7.1.77, nespecifična nukleozidna fosfotransferaza, nukleotid:3'-dezoksinukleozid 5'-fosfotransferaza) je enzim sa sistematskim imenom nukleotid:nukleozid 5'-fosfotransferaza.^[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

nukleotid + 2'-dezoksinukleozid ${\displaystyle \rightleftharpoons }$ nukleozid + 2'-dezoksinukleozid 5'-fosfat

Fenil fosfat i nukleozid 3'-fosfati mogu da budu donori.

Reference

1. Brunngraber, E.F. and Chargaff, E. (1967). „Purification and properties of a nucleoside phosphotransferase from carrot”. J. Biol. Chem. 242: 4834-4840. PMID 6061424. 
2. Prasher, D.C., Carr, M.C., Ives, D.H., Tsai, T.-C. and Frey, P.A. (1982). „Nucleoside phosphotransferase from barley. Characterization and evidence for ping pong kinetics involving phosphoryl enzyme”. J. Biol. Chem. 257: 4931-4939. PMID 6279651. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH Nucleoside+phosphotransferase