PROFILBARU.COM

Laurinska kiselina
	dodekanoinska kiselina
Drugi nazivi	n-Dodekanoinska kiselina; Dodecilinska kiselina; Dodekoinska kiselina; Laurostearinska kiselina; Vulvinska kiselina; 1-Undekankarboksilna kiselina; Duodecilinska kiselina;; C12:0 (Lipidni brojevi)
Identifikacija
CAS registarski broj	143-07-7
PubChem	3893
ChemSpider	3756
ChEMBL	CHEMBL108766
Jmol-3D slike	Slika 1
SMILES
	O=C(O)CCCCCCCCCCC
InChI
	InChI=1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14) ; Kod: POULHZVOKOAJMA-UHFFFAOYSA-N InChI=1/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14); Kod: POULHZVOKOAJMA-UHFFFAOYAP
Svojstva
Molekulska formula	C12H24O2
Molarna masa	200.31776
Agregatno stanje	beli prah
Miris	bligai miris na Pimenta racemosa
Gustina	0.880 g/cm3
Tačka topljenja	43.2 °C
Tačka ključanja	298.9 °C
Rastvorljivost u vodi	nerastvorna
Indeks prelamanja (nD)	1.423
Viskoznost	7.30 mPa·s na 323 K
Opasnost
NFPA 704	1 1 1
Tačka paljenja	≥ 110 °C
Srodna jedinjenja
Srodna jedinjenja	Gliceril laurat
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Lauric acid (dodekanoinska kiselina) je zasićena masna kiselina sa 12-ugljenika dugim lancom. Ona je beo prah sa slabim mirisom na Pimenta racemosa ili sapun.

Zastupljenost

Laurinska kiselina je glavna kiselina u kokosovom ulju i u ulju palmine koštice (koje ne treba mešati sa palminim uljem),^[6] i smatra se da ima antimikrobna svojstva.^[7]^[8]^[9]^[10] Ona je takođe prisutna u ljudskom mleku (6.2% totalne masnoće), kravljem mleku (2.9%), i kozjem mleku (3.1%).^[6]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Lide David R., ur. (2006). CRC Handbook of Chemistry and Physics (87th izd.). Boca Raton, FL: CRC Press. 0-8493-0487-3.
↑ ^6,0 ^6,1 Beare-Rogers, J.; Dieffenbacher, A.; Holm, J.V. (2001). „Lexicon of lipid nutrition (IUPAC Technical Report)”. Pure and Applied Chemistry 73 (4): 685–744. DOI:10.1351/pac200173040685.
↑ Hoffman KL, Han IY, Dawson PL (2001). „Antimicrobial effects of corn zein films impregnated with nisin, lauric acid, and EDTA”. J. Food Prot. 64 (6): 885–9. PMID 11403145.
↑ Ouattar B, Simard RE, Piett G, Bégin A, Holley RA (2000). „Inhibition of surface spoilage bacteria in processed meats by application of antimicrobial films prepared with chitosan”. Int. J. Food Microbiol. 62 (1–2): 139–48. DOI:10.1016/S0168-1605(00)00407-4. PMID 11139014.
↑ PL Dawson, GD Carl, JC Acton, and IY Han (2002-05-01). „Effect of lauric acid and nisin-impregnated soy-based films on the growth of Listeria monocytogenes on turkey bologna” (Free full text). Poultry Science 81 (5): 721–726. PMID 12033424. Arhivirano iz originala na datum 2009-01-13. Pristupljeno 2014-04-11.
↑ Alexey Ruzin and Richard P. Novick (May 2000). „Equivalence of Lauric Acid and Glycerol Monolaurate as Inhibitors of Signal Transduction in Staphylococcus aureus” (Free full text). J Bacteriol 182 (9): 2668–2671. DOI:10.1128/JB.182.9.2668-2671.2000. PMC 111339. PMID 10762277.

Literatura

Berner, Louise A. (1993). Defining the Role of Milkfat in Balanced Diets. In John E. Kinsella (Ed.) Advances in Food and Nutrition Research – Volume 37. Academic Press. pp. 159–166. ISBN 978-0-12-016437-0.
Kabara, Jon J. (1978). The Pharmacological Effect of Lipids. Champaign IL: American Oil Chemist's Society. ISBN 9991817697.
Kabara, Jon J. (2008). Fats Are Good for You and Other Secrets – How Saturated Fat and Cholesterol Actually Benefit the Body. North Atlantic Books. ISBN 1-55643-690-4.

Vanjske veze

Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[5] Lide David R., ur. (2006). CRC Handbook of Chemistry and Physics (87th izd.). Boca Raton, FL: CRC Press. 0-8493-0487-3.

[lexicon-6] 6,0 ^6,1 Beare-Rogers, J.; Dieffenbacher, A.; Holm, J.V. (2001). „Lexicon of lipid nutrition (IUPAC Technical Report)”. Pure and Applied Chemistry 73 (4): 685–744. DOI:10.1351/pac200173040685.

[7] Hoffman KL, Han IY, Dawson PL (2001). „Antimicrobial effects of corn zein films impregnated with nisin, lauric acid, and EDTA”. J. Food Prot. 64 (6): 885–9. PMID 11403145.

[8] Ouattar B, Simard RE, Piett G, Bégin A, Holley RA (2000). „Inhibition of surface spoilage bacteria in processed meats by application of antimicrobial films prepared with chitosan”. Int. J. Food Microbiol. 62 (1–2): 139–48. DOI:10.1016/S0168-1605(00)00407-4. PMID 11139014.

[9] PL Dawson, GD Carl, JC Acton, and IY Han (2002-05-01). „Effect of lauric acid and nisin-impregnated soy-based films on the growth of Listeria monocytogenes on turkey bologna” (Free full text). Poultry Science 81 (5): 721–726. PMID 12033424. Arhivirano iz originala na datum 2009-01-13. Pristupljeno 2014-04-11.

[10] Alexey Ruzin and Richard P. Novick (May 2000). „Equivalence of Lauric Acid and Glycerol Monolaurate as Inhibitors of Signal Transduction in Staphylococcus aureus” (Free full text). J Bacteriol 182 (9): 2668–2671. DOI:10.1128/JB.182.9.2668-2671.2000. PMC 111339. PMID 10762277.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]