Fitohromobilin:feredoksin oksidoreduktaza

Fitohromobilin:feredoksin oksidoreduktaza
Identifikatori
EC broj	1.3.7.4
CAS broj	138263-99-7
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Fitohromobilin:feredoksin oksidoreduktaza (EC 1.3.7.4, HY2, P&Phi, B sintaza, fitochromobilin sintaza) je enzim sa sistematskim imenom (3Z)-fitohromobilin:feredoksin oksidoreduktaza.^[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

(3Z)-fitohromobilin + oksidovani feredoksin ${\displaystyle \rightleftharpoons }$ biliverdin IX alfa + redukovani feredoksin

Ovaj enzim katalizuje dvoelektronsku redukciju biliverdina IX alfa. On može da koristi 2Fe-2S feredoksine iz brojnih izvora kao akceptor, mada ne i 4Fe-4S feredoksin iz Clostridium pasteurianum.

Reference

1. Frankenberg, N., Mukougawa, K., Kohchi, T. and Lagarias, J.C. (2001). „Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms”. Plant Cell 13: 965-978. PMID 11283349. 
2. McDowell, M.T. and Lagarias, J.C. (2001). „Purification and biochemical properties of phytochromobilin synthase from etiolated oat seedlings”. Plant Physiol. 126: 1546-1554. PMID 11500553. 
3. Terry, M.J., Wahleithner, J.A. and Lagarias, J.C. (1993). „Biosynthesis of the plant photoreceptor phytochrome”. Arch. Biochem. Biophys. 306: 1-15. PMID 8215388. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH Phytochromobilin:ferredoxin+oxidoreductase