DCTP difosfataza

DCTP difosfataza
Identifikatori
EC broj	3.6.1.12
CAS broj	9024-87-7
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

DCTP difosfataza (EC 3.6.1.12, dezoksicitidin-trifosfataza, dCTPaza, dCTP pirofosfataza, dezoksicitidinska trifosfataza, dezoksi-CTPaza, dCTPaza) je enzim sa sistematskim imenom dCTP nukleotidohidrolaza.^[1] Ovaj enzim katalizuje sledeću hemijsku reakciju

dCTP + H₂O ${\displaystyle \rightleftharpoons }$ dCMP + difosfat

Ovaj enzim takođe hidrolizuje dCDP do dCMP i fosfata.

Reference

1. Zimmerman, S.B. and Kornberg, A. (1961). „Deoxycytidine di- and triphosphate cleavage by an enzyme formed in bacteriophage-infected Escherichia coli”. J. Biol. Chem. 236: 1480-1486. PMID 13788541. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH DCTP+diphosphatase