Alkohol oksidaza

Alkohol oksidaza
Oktamer alkohol oksidaze (Pichia pastoris)
Identifikatori
EC broj	1.1.3.13
CAS broj	9073-63-6
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Alkohol oksidaza (EC 1.1.3.13, etanolna oksidaza) je enzim sa sistematskim imenom alkohol:kiseonik oksidoreduktaza.^[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

primarni alkohol + O₂ ${\displaystyle \rightleftharpoons }$ aldehid +H₂O₂

Ovaj enzim je flavoprotein (FAD). On deluje na niže primarne alkohole i na nezasićene alkohole. Neaktivan je na alkoholima razgranatog lanca i na sekundarnim alkoholima.

Reference

1. Janssen, F.W. and Ruelius, H.W. (1968). „Alcohol oxidase, a flavoprotein from several Basidiomycetes species. Crystallization by fractional precipitation with polyethylene glycol”. Biochim. Biophys. Acta 151: 330-342. PMID 5636370. 
2. Nishida, A., Ishihara, T. and Hiroi, T. (1987). „Studies on enzymes related to lignan biodegradation”. Baiomasu Henkan Keikaku Kenkyu Hokoku: 38-59. 
3. Suye, S. (1997). „Purification and properties of alcohol oxidase from Candida methanosorbosa M-2003”. Curr. Microbiol. 34: 374-377. PMID 9142745. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH Alcohol+oxidase