4-Hlorobenzoil-KoA dehalogenaza

4-Hlorobenzoil-KoA dehalogenaza
Identifikatori
EC broj	3.8.1.7
CAS broj	141583-18-8
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

4-Hlorobenzoil-KoA dehalogenaza (EC 3.8.1.7) je enzim sa sistematskim imenom 4-hlorobenzoil KoA hlorohidrolaza.^[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

4-hlorobenzoil-KoA + H₂O ${\displaystyle \rightleftharpoons }$ 4-hidroksibenzoil KoA + hlorid

Ovaj enzim je specifičan za dehalogenaciju u poziciji 4.

Reference

1. Chang, K.H., Liang, P.H., Beck, W., Scholten, J.D., Dunaway-Mariano, D. (1992). „Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3”. Biochemistry 31: 5605-5610. PMID 1610806. 
2. Crooks, G.P., Copley, S.D. (1994). „Purification and characterization of 4-chlorobenzoyl CoA dehalogenase from Arthrobacter sp. strain 4-CB1”. Biochemistry, 33: 11645-11649. PMID 7918379. 

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

• MeSH 4-chlorobenzoyl-CoA+dehalogenase