Бензилморфин

Бензилморфин
Изображение химической структуры
Изображение химической структуры
Химическое соединение
ИЮПАК (1S,5R,13R,14S,17R)- 10-(benzyloxy)- 4-methyl- 12-oxa- 4-azapentacyclo [9.6.1.01,13.05,17.07,18] octadeca- 7(18),8,10,15- tetraen- 14-ol
Брутто-формула C24H25NO3
Молярная масса 375.46 г/моль
CAS 14297-87-1
PubChem 5362507
DrugBank DB01573
Состав
Логотип Викисклада Медиафайлы на Викискладе

Бензилморфин — полусинтетический опиоидный наркотик, появившийся на международном рынке в 1896 году. Использовался почти так же, как кодеин и этилморфин, прежде всего, как умеренной силы анальгетик, при операциях на глазах, а также как лекарство от кашля. Он был доступен в Соединенных Штатах до 1914 года и использовался до 1960-х годов, но вышел из употребления, когда врачи стали отдавать предпочтение альтернативным производным опиатов. В России Бензилморфин входит в Список I Перечня наркотических средств, психотропных веществ и их прекурсоров, подлежащих контролю в Российской Федерации (оборот запрещён).

Бензилморфин используется в виде гидрохлорида (степень превращения свободного основания 0,91) и метилсульфоната (0,80) и имеет номер 9052 для административного контроля над веществами в США.

Литература

  • Merck Manual, 1900.
  • Merck Index, 1998.
  • Single Convention On Narcotic Drugs 1961 (United Nations).

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