Frederickson was taken as the first overall pick in the 1965 NFL draft by the New York Giants, playing six seasons for them before a knee injury forced his retirement in 1971. He was inducted in the College Football Hall of Fame in 1994.
Frederickson is referred to by Brian Piccolo (James Caan) as the man to beat in 1971's Brian's Song as both of them went to the same high school.[citation needed] In fact they went to different high schools, Frederickson to South Broward and Piccolo to Central Catholic (now St. Thomas Aquinas). Tucker went to the coveted Auburn University while Piccolo had to "settle" for Wake Forest.