Tryptophan synthase (indole-salvaging)

Tryptophan synthase (indole-salvaging)
Identifiers
EC no.	4.2.1.122
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Tryptophan synthase (indole-salvaging) (EC 4.2.1.122, tryptophan synthase beta2) is an enzyme with systematic name L-serine hydro-lyase (adding indole, L-tryptophan-forming).^[1] This enzyme catalyses the following chemical reaction

L-serine + indole ${\displaystyle \rightleftharpoons }$ L-tryptophan + H₂O

This enzyme salvages the lost indole to L-tryptophan.

References

1. Hettwer S, Sterner R (March 2002). "A novel tryptophan synthase β-subunit from the hyperthermophile Thermotoga maritima. Quaternary structure, steady-state kinetics, and putative physiological role". The Journal of Biological Chemistry. 277 (10): 8194–201. doi:10.1074/jbc.m111541200. PMID 11756459.

External links

• Tryptophan+synthase+(indole-salvaging) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)