The thyroid ima artery (thyroidea ima artery, arteria thyroidea ima, thyroid artery of Neubauer or the lowest thyroid artery) is an artery of the head and neck. It is an anatomical variant that, when present, supplies blood to the thyroid gland primarily, or the trachea, the parathyroid gland and the thymus gland (as thymica accessoria) in rare cases. It has also been reported to be a compensatory artery when one or both of the inferior thyroid arteries are absent, and in a few cases the only source of blood to the thyroid gland. Furthermore, it varies in origin, size, blood supply, and termination, and occurs in around 3.8% of the population and is 4.5 times more common in fetuses than in adults.[1] Because of the variations and rarity, it may lead to surgical complications, particularly during tracheostomy and other airway managements.
Structure
The thyroid ima artery is an embryonic artery and it occurs because of the failure of the vessel to close, remaining patent (open).[2]
It differs in size and ranges from as small as accessory thyroid arteries to the size of primary thyroid vessels. The diameter of the lumen of the artery ranges from 3 to 5 millimetres (0.12 to 0.20 in).[5] The artery may be present as an accessory thyroid artery, but sometimes appears to compensate for incompetence or absence of one or more main thyroid vessels.[6] Since it begins from below the thyroid gland and ascends upwards, it is mostly associated with absence or reduced size of the inferior thyroid arteries.[7] In such cases, it is known as the accessory inferior thyroid artery.[5][6] In rare cases, the artery has been seen to be compensating for absence of one or both superior thyroid arteries.[8]
In cases where the length of the thyroid ima artery is shorter, the artery ends by supplying the thymus gland and is known as thymica accessoria.[5]
Function
When present, the thyroid ima's chief supply is the thyroid gland, though it also supplies the trachea. The artery may extend and supply the parathyroid glands. An infrequently observed artery, it is more frequently reported in the context of enlarged parathyroid glands (parathyroid adenomas). The artery ends by supplying the thyroid gland, or the parathyroid glands, as a single unit or as multiple branches.[6][9] The artery is also found to be the only supply of the parathyroid gland in rare cases.[6]
Clinical significance
The artery is only present in approximately 3–10% of the population.[10][11] Thyroid ima artery is of surgical importance; due to its relatively small size and infrequent presence it can cause complications such as severe bleeding.[12] Knowledge of occurrence of the artery is especially important during tracheostomy, sternotomy and thyroidectomy.[5] Because the artery is smaller than the other thyroid vessels, and having an origin from one of the bigger vessels, a brisk cut while performing the surgery may cause complications such as severe hemorrhage and significant blood loss.[13] The artery, if dissected, may draw back into the mediastinum and further complicate the condition by causing hemorrhage and clots in the thoracic cavity.[14]
History
The thyroid ima artery was first defined by German anatomist Johann Ernst Neubauer [de] in the year 1772. Hence, it was named the thyroid artery of Neubauer.[15] The artery originates lower than the inferior thyroid arteries, so it is also known as the lowest thyroid artery.[10][11]Arteria thyroidea ima is the Latin name of the artery.[11][3]
Other animals
The presence of thyroid ima artery is also observed in other higher primates. The artery has been reported in gorillas, gibbons, macaques and gray langurs. Variations in the origin were also seen; it was found to originate from the aorta in the thorax, or the carotid in the neck.[16]
References
^Yurasakpong, Laphatrada; Nantasenamat, Chanin; Janta, Sirorat; Eiamratchanee, Pinthusorn; Coey, James; Chaiyamoon, Arada; Kruepunga, Nutmethee; Senarai, Thanyaporn; Langer, Martin Franz; Meemon, Krai; Suwannakhan, Athikhun (2022). "The decreasing prevalence of the thyroid ima artery: a systematic review and machine learning assisted meta-analysis". Annals of Anatomy - Anatomischer Anzeiger. 239: 151803. doi:10.1016/j.aanat.2021.151803. ISSN0940-9602. PMID34265384.
^ abHenry Gray (2015). Susan Standring (ed.). Gray's Anatomy: The Anatomical Basis of Clinical Practice (41st ed.). Elsevier Health Sciences. p. 1026. ISBN978-0-7020-6851-5.
^ abcdG. Wyatt Pratt (1916). "The Thyroidea Ima Artery". Journal of Anatomy. 50 (Pt 3): 239–242.
^ abcdKrudy A.G.; Doppman J.L.; Brennan M.F. (1980). "The significance of the thyroidea ima artery in arteriographic localization of parathyroid adenomas". Radiology. 136 (1): 45–51. doi:10.1148/radiology.136.1.7384523. PMID7384523.
^Choi, Yeo-Kyu Youn, Kyu Eun Lee, June Young (2014). Color atlas of thyroid surgery : open, endoscopic and robotic procedures (Aufl. 2014 ed.). Berlin, Heidelberg: Springer Berlin Heidelberg. p. 3. ISBN978-3-642-37262-9.{{cite book}}: CS1 maint: multiple names: authors list (link)
^Yilmaz E.; Celik H.H.; Durgun B.; Atasever A.; Ilgi S. (1993). "Arteria thyroidea ima arising from the brachiocephalic trunk with bilateral absence of inferior thyroid arteries: a case report". Surgical and Radiologic Anatomy. 15 (3): 197–199. doi:10.1007/bf01627705. PMID8235962. S2CID32274136.
^Beaumanoir (1882). "Preséntation de pièces anatomiques: artère thyroïdienne de Neubauer". Bulletins et Mémoires de la Société Anatomique (in French). 4: 316–317.
^ abBD Chaurasia (2012). Garg, Krishna; Mittal, PS; Chandrupatla, Mrudula (eds.). BD Chaurasia's Human Anatomy: Head-Neck and Brain. Vol. 3 (6th ed.). CBS Publishers. p. 143. ISBN978-81-239-2332-1.
^Vishram Singh (2012). P. Mahalingam (ed.). Clinical and Surgical Anatomy (2nd ed.). Elsevier Health Sciences. pp. 301–303. ISBN978-81-312-0303-3.
^N. Anthony Moore; William A. Roy (2010). Rapid Review Gross and Developmental Anatomy. Elsevier Health Sciences. p. 220. ISBN978-0-323-08048-4.
^C. Neubauer (1786). De arteria thyreoidea ima rariare arteriae innominate ramo. pp. 291–296, 309–314.
^Arthur Keith (1895). "The Modes of Origin of the Carotid and Subclavian Arteries from the Arch of the Aorta in Some of the Higher Primates". Journal of Anatomy and Physiology. 29 (Pt 3): 455.