Khan was a nurse at Jefferson Abington Hospital from 2005 to 2010. Between 2011 and 2014, he worked as a nurse practitioner in Washington, D.C. In 2015, Khan began working in the same role at Abbottsford-Falls Health Center in Philadelphia.[8] During his studies at University of Pennsylvania, Khan was president of the Pennsylvania State Nurses Association.[7]
At the onset of the COVID-19 pandemic in Philadelphia, Khan penned at op-ed in The Philadelphia Inquirer where he lamented the lack of PPE at his health center and criticized the administration of President Donald Trump for perceived inaction.[3]
In an effort to avoid wasting COVID vaccines on the verge of expiring, Khan took it upon himself to individually visit and inoculate over 900 homebound residents in Philadelphia.[9][10][11] Khan's delivery of "angel doses" garnered him national media attention and resulted in the established of a mobile vaccine clinic and more in-home inoculations.[6] A documentary titled "Angel Dose" from filmmaker Sami Khan was also made chronicling Khan's deliveries.[12]
Khan is both the first Pakistani-American lawmaker and first advanced practice nurse ever elected to the Pennsylvania legislature.[16]
In 2024, Khan led a group of Pennsylvania lawmakers to propose a bill to outlaw the use of deepfakes by political campaigns.[17]
The same year, Khan proposed legislation that would repeal laws that require abortion centers to operate within the same standards as surgical centers.[18] He contends these laws, known as Targeted Regulation of Abortion Providers laws, or TARP laws, are unnecessary, excessive, and only serve to close down abortion centers.[19]
Khan co-signed a statement expressing support for pro-Palestinian student protesters and criticizing the police response to the protest encampments.[20]
^ ab"State Rep". Philadelphia Election Results. Office of the Philadelphia City Commissioners. November 27, 2022. Archived from the original on December 3, 2022. Retrieved January 24, 2023.{{cite web}}: CS1 maint: unfit URL (link)
^"State Rep". Philadelphia Election Results. Office of the Philadelphia City Commissioners. May 31, 2022. Archived from the original on June 8, 2022. Retrieved January 24, 2023.{{cite web}}: CS1 maint: unfit URL (link)