T2-induced deoxynucleotide kinase

T2-induced deoxynucleotide kinase
Identifiers
EC no.	2.7.4.12
CAS no.	37278-99-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a T2-induced deoxynucleotide kinase (EC 2.7.4.12) is an enzyme that catalyzes the chemical reaction

ATP + dGMP (or dTMP) ${\displaystyle \rightleftharpoons }$ ADP + dGDP (or dTDP)

The 3 substrates of this enzyme are ATP, dGMP, and dTMP, whereas its 3 products are ADP, dGDP, and dTDP.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:(d)NMP phosphotransferase.

References

• BELLO LJ, BESSMAN MJ (1963). "The enzymology of virus-infected bacteria. IV. Purification and properties of the deoxynucleotide kinase induced by bacteriophage T2". J. Biol. Chem. 238: 1777–87. PMID 13967158.