In the early 1960s, Clark while living in London began appearing on British television, including guest appearances on The Plane Makers, The Sentimental Agent and The Benny Hill Show. She made her debut on the London stage in Poor Bitos. The play and Clark received good reviews but news from home about her father, who had fallen ill, led her back to Canada.[4] She returned to Canada in 1965, when she appeared in a number of episodes of the anthology series Festival.
Clark starred in the 1975 television movie, Babe, playing multi-sport athlete Babe Didrikson Zaharias. Her performance won her an Emmy in 1976.[6] In 1976, she starred in a three-hour made-for-television movie biography of the aviator Amelia Earhart which also covered her marriage to noted publisher G. P. Putnam; she received an Emmy nomination for Best Actress. She posed topless for Playboy in the February 1973 issue pictorial entitled "The Ziegfeld Girls: A dazzling review starring the talking pictures' own Susan Clark".
She married American football player turned actor Alex Karras in 1980. They met when they co-starred in Babe (and he played her husband,[6] professional wrestler George Zaharias). They later co-starred on the popular primetime sitcom Webster together, portraying husband and wife. Their daughter Katie was born in 1980.
Clark and Karras remained married for 32 years until his death on October 10, 2012.[7]
