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kinase-associated protein 1 is an enzyme that in humans is encoded by the SKP1 gene. This gene encodes a protein that is a member of the SCF ubiquitin ligase...
Click to read more »In enzymology, a [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase (EC 2.4.1.229) is an enzyme that catalyzes the chemical reaction UDP-N-acetylglucosamine...
Click to read more »regulated through cyclin-CDK-mediated phosphorylation of target proteins. Skp1 – Skp1 is an adaptor protein that is essential for the recognition and binding...
Click to read more »of NCAM1, TGF-β2, Skp1, neurotrophin 3, and artemin factors by 1.4-fold, 1.4-fold, 1.5-fold, 1.8-fold, and 3.2-fold respectively. Skp1 may increase the...
Click to read more »consisting of three alpha-helices, interacts directly with the SCF protein Skp1. F-box domains commonly exist in proteins in cancer with other protein–protein...
Click to read more »originally found to be conjugated to Cdc53, a cullin component of the SCF (Skp1-Cdc53/CUL1-F-box protein) E3 Ub ligase complex in Saccharomyces cerevisiae...
Click to read more »degradation and protein ubiquitination. This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which often—but not always—recognize substrates in a...
Click to read more »Suppressor of G2 allele of SKP1 homolog is a protein that in humans is encoded by the SUGT1 gene. This gene is homologous to the yeast gene SGT1, which...
Click to read more »complex (APC) and the SCF complex (Skp1-Cullin-F-box protein complex). SCF complexes consist of four proteins: Rbx1, Cul1, Skp1, which are invariant among SCF...
Click to read more »formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through...
Click to read more »COMPLEX WITH METAVANADATE 2ass: Crystal structure of the Skp1-Skp2-Cks1 complex 2ast: Crystal structure of Skp1-Skp2-Cks1 in complex with a p27 peptide...
Click to read more »formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »RJ (July 2001). "Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation". Proceedings of...
Click to read more »RJ (July 2001). "Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation". Proceedings of...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »Deshaies, R.J. (2001). Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation. Proc. Natl. Acad...
Click to read more »Yu ZK, Gervais JL, Zhang H (Sep 1998). "Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21CIP1/WAF1 and cyclin D proteins". Proceedings...
Click to read more »discovered in Drosophila and other insects. They are a part of the SCF (SKP1–Cullin1–F-box protein) family of ubiquitin ligases that plays a huge role...
Click to read more »of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »EC 2.4.1.228: lactosylceramide 4-α-galactosyltransferase EC 2.4.1.229: [Skp1-protein]-hydroxyproline N-acetylglucosaminyltransferase EC 2.4.1.230: kojibiose...
Click to read more »Phosphatidylinositol 3 kinase phosphorylates p27 (or p16 or p21) and SCF/Skp1. The phosphorylation of p27 inhibits p27's ability to bind Cdk4, thus freeing...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (Skp1-Cul1-F-box protein), which often, but not always, recognize substrates in...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »019 Zheng, N., Schulman, B., Song, L. et al. Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex. Nature 416, 703–709 (2002). https://doi...
Click to read more »of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through...
Click to read more »endonuclease domain. FBNYV produces the small protein Clink which binds to SKP1 and Prb proteins in plants. Timchenko et al. 2006 demonstrate that Clink...
Click to read more »"Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A". Cell Growth & Differentiation...
Click to read more »yeast two-hybrid screen searching for proteins that bind to the SCF subunit Skp1. Several studies using Cryo-Electron Microscopy (Cryo-EM) and Nuclear Magnetic...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they...
Click to read more »Function in a telecommunications network Small carbonaceous fossil SCF-complex (Skp1/Cul1/F-box complex), a ubiquitin ligase Supercritical fluid Standard cubic...
Click to read more »one of the four subunits of ubiquitin-protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »Pan ZQ (Dec 2002). "CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex". Proceedings of the National Academy of...
Click to read more »anaphase promoting complex (APC), an E3 ubiquitin ligase. The APC and the Skp1/Cul1/F-box protein complex (SCF complex) are the two key regulators of cyclin...
Click to read more »division control protein 4) is a substrate recognition component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which acts as a mediator of...
Click to read more »of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which are part of the ubiquitin-proteosome system (UPS). The...
Click to read more »of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »(December 2002). "CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex". Proceedings of the National Academy of...
Click to read more »substrate. The anaphase-promoting complex (APC) and the SCF complex (for Skp1-Cullin-F-box protein complex) are two examples of multi-subunit E3s involved...
Click to read more »is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein...
Click to read more »of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »though exclusively expressed in the nuclear subcellular location. NIPA is a skp1 cullin F-box (SCF)-type ubiquitin E3 ligase (SCFNIPA) complex protein involved...
Click to read more »GLMN gene. This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development...
Click to read more »constitute one of the four subunits of the ubiquitin ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »transcription of genes . It contains a N-terminal BTB/POZ domain (IPR000210) or a SKP1/BTB/POZ domain (IPR011333), and three C-terminal zinc fingers, Znf_C2H2_sf...
Click to read more »of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein". Proc. Natl. Acad. Sci. U.S.A. 96 (17): 9533–8. Bibcode:1999PNAS...
Click to read more »Pan ZQ (Dec 2002). "CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex". Proc. Natl. Acad. Sci. U.S.A. 99 (26):...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »Kay; Ma, Lei; Goebl, Mark; Harper, J. Wade; Elledge, Stephen J. (1996). "SKP1 Connects Cell Cycle Regulators to the Ubiquitin Proteolysis Machinery through...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (Skp1-Cul1-F-box protein), which often, but not always, recognize substrates in...
Click to read more »P12757 14846 SKOR1 HGNC:21326; P84550 14847 SKOR2 HGNC:32695; Q2VWA4 14848 SKP1 HGNC:10899; P63208 14849 SKP2 HGNC:10901; Q13309 14850 SLA HGNC:10902; Q13239...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »AW, Poon RY (January 1999). "Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2". Molecular and Cellular Biology. 19 (1): 635–45....
Click to read more »other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 ubiquitin ligase independently of peroxisome proliferator-activated...
Click to read more »Pan ZQ (Dec 2002). "CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex". Proc Natl Acad Sci U S A. 99 (26): 16601–6...
Click to read more »β-transducin repeat-containing protein 1/2 (β-TrCP1/2) F-box protein-containing SKP1/Cul1/F-box protein complex "Gene: wee1 / SPCC18B5.03". PomBase. Nurse P (December...
Click to read more »Franowo PFD – Stary Młyn 824 Pokrzywno – Poznań Franowo PFD 825 Jarocin SKP1 – Jarocin R285 826 Jarocin R10 – Jarocin R16 T111 827 Kostrzyn R5 – Kostrzyn...
Click to read more »RJ (July 2001). "Protacs: chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation". Proceedings of...
Click to read more »subunits of a ubiquitin ligase complex called SKP1-CUL1-F-box-protein, which includes the proteins CUL1, SKP1, and RBX1. The FBXL3 protein plays a role in...
Click to read more »adaptor protein, it links the E3 ubiquitin ligase activity of Siah-1 with Skp1 and Ebi F-Box protein in the degradation of beta-catenin, a transcriptional...
Click to read more »of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »polyubiquitylation of p27 by the SCFSKP2 kinase associated protein 1 (Skp1) and 2 (Skp2). SKP1 and Skp2 degrades p27 after it has been phosphorylated at threonine...
Click to read more »phosphorylated by DBT is recognized by the Slimb protein. Slimb is a component of the Skp1/Cullin/F-box protein (SCF) ubiquitin ligase complex, which marks proteins...
Click to read more »(December 2002). "CUL7: A DOC domain-containing cullin selectively binds Skp1.Fbx29 to form an SCF-like complex". Proceedings of the National Academy of...
Click to read more »"NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases". Mol. Cell. 10 (6): 1511–8. doi:10.1016/S1097-2765(02)00783-9...
Click to read more »"NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases". Molecular Cell. 10 (6): 1511–8. doi:10.1016/S1097-2765(02)00783-9...
Click to read more », Jhangiani, S., Stankiewicz, P., . . . Gajecka, M. (2016). Variants in SKP1, PROB1 and IL17B genes at keratoconus 5q31.1–q35.3 susceptibility locus identified...
Click to read more »of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein". Proc. Natl. Acad. Sci. U.S.A. 96 (17): 9533–8. Bibcode:1999PNAS...
Click to read more »one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination...
Click to read more »