The diocese was created on 20 December 1878, when the then Diocese of Beverley, which covered the whole of Yorkshire, was divided into the Diocese of Middlesbrough, covering the North and East Ridings of Yorkshire and those parishes in the City of York to the north of the River Ouse, and the Diocese of Leeds, covering the West Riding of Yorkshire and those parishes in the City of York to the south of the River Ouse. In 1982 the two York parishes south of the River Ouse were ceded to the Diocese of Middlesbrough to unite the City of York under one bishop. The parish of Howden was transferred from Middlesbrough to the Leeds diocese in 2004.
St Mary's Cathedral, Coulby Newham • Sacred Heart and St Patrick, Middlesbrough • St Joseph, Middlesbrough • St Thomas More, Middlesbrough • Holy Name of Mary, Middlesbrough • St Francis of Assisi, Middlesbrough • St Alphonsus, North Ormesby • St Gabriel, Ormesby • Corpus Christi, Middlesbrough • St Clare of Assisi, Middlesbrough • St Andrew's Parish, Teesville • St Pius X, Middlesbrough • St Bernadette's, Nunthorpe • St Joseph, Stokesley • St Mary, Crathorne • St Thérèse of Lisieux, Ingleby Barwick • St Patrick, Thornaby • Christ the King, Thornaby • Ss Mary and Romuald, Yarm • Our Lady of Mount Grace, Osmotherley • Sacred Heart, Redcar • St Augustine, Redcar • St Bede, Marske-by-the-Sea • Our Lady of Lourdes, Saltburn • St Anthony of Padua, Brotton • St Paulinus, Guisborough • Ss Joseph & Cuthbert, Loftus • Sacred Heart, Northallerton • Ss Mary & Joseph, Bedale • All Saints, Thirsk • Ss Joseph & Francis Xavier, Richmond • Ss Peter & Paul, Leyburn • St Mary's, Wycliffe • Ss Simon and Jude, Ulshaw Bridge • St Bede, Catterick • Hawes • St Joan of Arc, Catterick Garrison • St Margaret Clitherow, Great Ayton
Ss Mary and Joseph, Pocklington • St John of Beverley, Beverley • Our Lady of Perpetual Help, Market Weighton • St John the Baptist, Holme-on-Spalding Moor • Our Lady & St Peter, Bridlington • Our Lady & St Edward, Driffield • Holy Cross, Cottingham • St Anthony and Our Lady of Mercy, Hull • Our Lady of Lourdes and St. Peter Chanel, Hull • St Charles Borromeo, Hull • St Joseph, Hull • Holy Name, Hull (closed c.2012) • St Vincent De Paul, Hull • Corpus Christi, Hull • St Wilfrid, Hull • Our Lady of Lourdes, Hessle • St Willibrord University Chaplaincy, Hull • Sacred Heart, Hull • St Bede, Hull • St Stephen, Hull • St Francis of Assisi, Hull • St Mary, Queen of Martyrs, Hull • Ss Mary & Joseph, Hedon • Sacred Heart, Hornsea • Ss Peter & John Fisher, Withernsea • Most Holy Sacrament, Marton
Nicholas Postgate Catholic Academy trust (NPCAT) is a multi-academy trust (MAT) that operates thirty-eight schools (five secondary schools and thirty-two primary schools) across the Roman Catholic Diocese of Middlesbrough. It is an exempt charity, regulated by the Department for Education.[2][3]
In 2022, NPCAT launched a football academy to cater for rising talent in Teesside, North Yorkshire and the City of York.
Upon the dissolving of Saint Margaret Clitherow Catholic Academy Trust, NPCAT gained schools in the central vicariate of the diocese which had previously administered by SMCCAT.