Sowdhamini's research is in the fields of computational studies of Protein Science as well as genome sequencing and she is reported to have done advanced research in the code development for studying Protein folding and unfolding.[6] She leads a group of scientists engaged in the computational studies of proteins with regard to their random rearrangements during evolution[7] and they have carried out genome surveys of several protein families and superfamilies.[8] Her team was successful in preparing the draft genome of Ocimum tenuiflorum (commonly known as Tulsi), a plant with medicinal properties, for the first time which assisted in identifying the genes responsible for the production of Ursolic acid, a triterpenoid and Eugenol, a phenylpropanoid, compounds responsible for the medicinal properties of the plant.[9][10] She was the lead developer of 3DSwap, a database of 3D domain-swapped proteins.[11] Besides, along with James Spudich of the Stanford University and Henrik Flyvbjerg of the Technical University of Denmark, she led the project for studying coiled coil interactions in proteins, a collaborative project of the two institutions and the National Centre for Biological Sciences.[12] Her studies have been documented by way of a number of articles[13][note 2] and ResearchGate, an online repository of scientific articles has listed 427 of them.[14] She sits in the editorial board of Bioinformation journal[15] and has also mentored many post-graduate, doctoral ad post-doctoral scholars in their research.[16][17][18]
^"Indian fellow". Indian National Science Academy. 21 December 2017. Archived from the original on 23 December 2017. Retrieved 21 December 2017.
^"Faculty – NCBS". National Centre for Biological Sciences. 26 December 2017. Retrieved 26 December 2017.
^"Faculty – InStem". Institute for Stem Cell Biology and Regenerative Medicine. 26 December 2017. Retrieved 26 December 2017.
^Phillip R. Westmoreland; Peter A. Kollman; Anne M. Chaka, Peter T. Cummings, Keiji Morokuma, Matthew Neurock, Ellen B. Stechel, Priya Vashishta (17 April 2013). Applying Molecular and Materials Modeling. Springer Science & Business Media. pp. 184–. ISBN978-94-017-0765-7.{{cite book}}: CS1 maint: multiple names: authors list (link)