Presqualene diphosphate synthase

Presqualene diphosphate synthase
Identifiers
EC no.	2.5.1.103
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Presqualene diphosphate synthase (EC 2.5.1.103, SSL-1 (gene)) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:(2E,6E)-farnesyl-diphosphate farnesyltransferase (presqualene diphosphate forming).^[1] This enzyme catalyses the following chemical reaction

2 (2E,6E)-farnesyl diphosphate ${\displaystyle \rightleftharpoons }$ presqualene diphosphate + diphosphate

This enzyme is isolated from the green alga Botryococcus braunii BOT22.

References

1. Niehaus TD, Okada S, Devarenne TP, Watt DS, Sviripa V, Chappell J (2011). "Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii". Proc. Natl. Acad. Sci. USA. 108 (30): 12260–12265. Bibcode:2011PNAS..10812260N. doi:10.1073/pnas.1106222108. PMC 3145686. PMID 21746901.

External links

• Presqualene+diphosphate+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)