Poly(ribitol-phosphate) N-acetylglucosaminyl-transferase

poly(ribitol-phosphate) N-acetylglucosaminyltransferase
Identifiers
EC no.	2.4.1.70
CAS no.	37277-71-7
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a poly(ribitol-phosphate) N-acetylglucosaminyl-transferase (EC 2.4.1.70) is an enzyme that catalyzes the chemical reaction

UDP-N-acetyl-D-glucosamine + poly(ribitol phosphate) ${\displaystyle \rightleftharpoons }$ UDP + (N-acetyl-D-glucosaminyl)poly(ribitol phosphate)

Thus, the two substrates of this enzyme are UDP-N-acetyl-D-glucosamine and poly(ribitol phosphate), whereas its two products are UDP and (N-acetyl-D-glucosaminyl)poly(ribitol phosphate).

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-N-acetyl-D-glucosamine:poly(ribitol-phosphate) N-acetyl-D-glucosaminyltransferase. Other names in common use include UDP acetylglucosamine-poly(ribitol phosphate), acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-poly(ribitol phosphate), and acetylglucosaminyltransferase.

References

• Nathenson SG, Ishimoto N, Strominger JL (1966). "UDP-N-acetylglucosamine: Polyribitol phosphate N-acetylglucosaminyltransferases from Staphylococcus aureus". Complex Carbohydrates. Methods in Enzymology. Vol. 8. pp. 426–429. doi:10.1016/0076-6879(66)08079-0. ISBN 978-0-12-181808-1.