Clark signed with the Detroit Tigers after being selected with their first-round pick in the 1986 Major League Baseball Draft out of high school, and made his major league debut with the Tigers in 1992. He was sent off to the San Diego Padres the following year, and hit .313 with 9 home runs in 102 games. He continued to play part-time before being released by the Boston Red Sox in 1996. He joined the Kintetsu Buffaloes in the Japanese Pacific League in 1997, and hit 23 home runs with a .331 batting average (second in the league after Ichiro Suzuki) in his first year to win the Best Nine Award at first base. He hit 48 doubles in 1998, which was the Japanese single-season record until Yoshitomo Tani broke it in 2001, and ended with a .320 batting average, with 31 home runs and 114 RBIs to win his second consecutive Best Nine Award. His production decreased in 1999, but he still won a third Best Nine Award at designated hitter. In 2000, he missed over half of the season after being hit by a pitch, and was released at the end of the year.