Born and raised in New Orleans to a politician mother and school administrator father, Clarkson earned a degree in drama from Fordham University before attending the Yale School of Drama, where she graduated with a Master of Fine Arts degree. She made her feature film debut in Brian De Palma's mob drama The Untouchables (1987), followed by a supporting role in Buddy Van Horn's The Dead Pool (1988). After appearing in minor roles in the early and mid-1990s, she garnered critical attention for her portrayal of a drug-addicted actress in the independent drama High Art (1998). She appeared in numerous supporting roles in such films as The Green Mile (1999), The Pledge (2001), Far from Heaven (2002), and Dogville (2003).
Clarkson returned to Broadway in 1989 in Eastern Standard, portraying a Wall Street investment counselor whose brother (played by Kevin Conroy) is diagnosed with AIDS; the play ran from January to March of that year.[9]
Clarkson has stated that in the early 1990s, she went through a turbulent period in her career and was unable to find significant work.[11] She had a small role in Jumanji (1995)[12] before being cast in the independent drama High Art (1998), portraying a drug-addicted German actress in New York City.[7] Her performance earned her an Independent Spirit Award nomination for Best Supporting Actress.[13]
In 1998, Clarkson had a small role in the critically acclaimed independent romantic comedy Playing By Heart, playing a woman at a bar who listens to a false story told by a man (Dennis Quaid) as part of his improv class. In 1999, Clarkson appeared in a supporting role as an ailing wife of a prison warden in The Green Mile, which was nominated for a Screen Actors Guild Award for Best Ensemble Cast.[13] The same year, she had a supporting part in the romantic comedy Simply Irresistible (1999), followed by a supporting part in Stanley Tucci's biopic Joe Gould's Secret (2000).[14] Next, she portrayed a single mother in the drama The Safety of Objects (2001), and had a supporting role opposite Jack Nicholson in the Sean Penn-directed thriller The Pledge (2001), playing the mother of a murder victim.[15] She also had a leading role in the independent horror filmWendigo (2001), directed by Larry Fessenden,[16] and in the comedy Welcome to Collinwood (2002).[17]Roger Ebert praised the performances in the former, noting: "The actors [in Wendigo] have an unforced, natural quality that looks easy but is hard to do."[16] In 2001 she had a recurring role on Frasier as Claire French, who dated Frasier Crane played by Kelsey Grammer.
Following these critical successes, Clarkson had a lead role opposite Kurt Russell in the sports docudrama Miracle (2004), about the U.S. hockey team defeating the heavily favored Soviets in the 1980 Olympics, and played the wife of a news correspondent (Robert Downey Jr.) in George Clooney's historical drama Good Night, and Good Luck (2005), about the conflict between journalist Edward R. Murrow and Joseph McCarthy.[24] She then starred as the wife of a Hollywood studio executive in the independent drama The Dying Gaul (2005).[25] 2006 saw the release of The Woods, a supernatural horror film shot in 2003[26] in which she portrayed the headmistress of a girls' boarding school. The same year, she portrayed Sadie Burke in All the King's Men, set in her native New Orleans.[27]
In 2010, Clarkson appeared opposite Leonardo DiCaprio in the Martin Scorsese-directed thriller Shutter Island, playing a woman escaped from a psychiatric institution.[32] Recounting being cast in the part, Clarkson said: "I got the call that every actor lives for. 'Patty, Martin Scorsese is thinking of casting you in his new movie.' And I do what I call the little 'Martin Scorsese dance' around my apartment. I think I was in my underwear or pajamas. It's a call you live for. Then I hear back, 'But it's just one scene.' So then I'm dancing a little lower. Then I hear, 'It's you and Leonardo DiCaprio in a cave,' and then I'm dancing again."[32] The film was a box office hit, and Scorsese's highest-grossing film at the time.[33]
Clarkson subsequently had roles in two independent films: Legendary and Main Street (both 2010), before appearing in two mainstream comedies directed by Will Gluck: Easy A (2010), as the mother of a troubled high school student (Emma Stone), and as the mother of an executive recruiter (Mila Kunis) in Friends with Benefits (2011).[34] She also appeared in the romantic drama One Day (2011) as the mother of a college student in Scotland (portrayed by Jim Sturgess),[35] and guest-starred on two episodes of the comedy series Parks and Recreation.[17] In 2013, she had a supporting role in the thriller The East (2013) as the leader of a private intelligence firm.[36]
She subsequently starred in the science fiction film Jonathan, involving two brothers who alternately share a single body,[45] and the psychological horror film Delirium, which was released directly-to-DVD.[46] Clarkson starred opposite Amy Adams in the psychological drama miniseriesSharp Objects (2018), portraying the wealthy mother of an alcoholic reporter (Adams) investigating a murder in their Missouri town.[47] For her performance in the series, Clarkson won a Golden Globe Award for Best Supporting Actress in a Series, Miniseries or Television Film.
In 2023, Clarkson assumed the lead role in the espionage thriller series Gray, co-produced by AGC Television and Lionsgate Films. The series chronicles CIA operative Cornelia Gray's return to her former life after two decades in hiding, amidst revelations of a mole within the spy network she once belonged to.[48][49]
Clarkson resides in New York City.[21] In 2007, she purchased a loft in Greenwich Village for US$1.5million (equivalent to $2.2million in 2023).[51] She listed it for $2.5million (equivalent to $3million in 2023) in November 2018.[52] She has never married and has no children,[53] stating in a 2013 interview, "I've never wanted to marry, I've never wanted children—I was born without that gene."[54] Three of Clarkson's four sisters have children and she is very close to her nieces and nephews.[55] One of her nephews, Mac Alsfeld,[56] is an actor, writer and director.[57]
She made her film debut in The Untouchables (1987), followed by a supporting role in The Dead Pool (1988). She appeared in numerous supporting roles in such films as The Green Mile (1999), The Pledge (2001), Far from Heaven (2002), Dogville (2003), The Station Agent (2003), Pieces of April (2003), Good Night, and Good Luck (2005), Lars and the Real Girl (2007), and Elegy (2008). She also appeared in Woody Allen films Vicky Cristina Barcelona (2008) and Whatever Works (2009). In 2010, Clarkson had a supporting role in the thriller Shutter Island, followed by roles in the comedies Easy A and Friends with Benefits. She portrayed Ava Paige in The Maze Runner (2014) and its two sequels. In 2017, she co-starred in Sally Potter's drama The Party and guest-starred on the Netflix series House of Cards. She co-starred with Amy Adams on the HBO miniseries Sharp Objects in 2018.
^Wiater, Stanley; Golden, Christopher; Wagner, Hank (2006). The Complete Stephen King Universe: A Guide to the Worlds of Stephen King. New York: Macmillan. p. 190. ISBN978-0-312-32490-2.
^Woodard, Josef (November 1, 2007). "Lars and the Real Girl". The Santa Barbara Independent. Santa Barbara, California. Archived from the original on December 9, 2018. Retrieved December 9, 2018.
^Mathieson, Craig (March 18, 2024). "Past becomes present in a role Clarkson couldn't refuse - Thriller". The Sydney Morning Herald. Sydney, Australia. p. 6.
^"Gray". IMDb.com. 2023. Retrieved March 18, 2024.