Falco was born in the New York City borough of Brooklyn on July 5, 1963, the daughter of Judith Anderson, an actress, and Frank Falco, a jazz drummer who later worked for an advertising agency.[8][9] Her father was of Italian descent and her mother had Swedish, English and Cornish (1/16th) ancestry.[10][11][12] She has two brothers, Joseph and Paul, and a sister, Ruth. Her uncle is novelist, playwright, and poet Edward Falco. In 2012, Falco was the subject of an episode of Who Do You Think You Are? which focused on one of her ancestors, a Cornish master mariner from Penzance who was born at sea and died in 1840.[13][14][15]
Early in her career, Falco made appearances on television shows like Law & Order and Homicide: Life on the Street. Tom Fontana, executive producer of Homicide, cast Falco as Eva Thormann, the wife of an injured police officer, after watching Falco's performance in Laws of Gravity, a 1992 film directed by Nick Gomez. Fontana said of her, "She's an actress who's unadorned by any embroidery. She does everything with such simplicity and honesty, it's breathtaking."[20] A struggling actress at the time, Falco said her salary from these television episodes paid for one month's worth of rent.[21] She debuted on the big screen in 1987's Sweet Lorraine starring Maureen Stapleton.[22]
Later, she had a small speaking role in the Woody Allen comedy film Bullets Over Broadway (1994). Her friendship with former SUNY Purchase classmate Eric Mendelsohn, who was the assistant to Allen's costume designer, Jeffrey Kurland, helped her to be cast in the role. Mendelsohn went on to direct Falco in his feature film Judy Berlin, for which he won Best Director honors at the Sundance Film Festival. Falco went on to star in Mendelsohn's next film 3 Backyards, for which he won Best Director a second time.[23]
As of 2008, Falco, The X-Files star Gillian Anderson, Ugly Betty star America Ferrera, and 30 Rock's Tina Fey were the only actresses to have received a Golden Globe, an Emmy, and a SAG Award in the same year. Falco won these awards in 2003 for her performance as Carmela Soprano during the fourth season of The Sopranos. In the show's final season Alessandra Stanley of The New York Times wrote, "The series has always distinguished itself by the quality of its actors, but this season Ms. Falco depicts even more deeply than before, if that's possible, the full range of a mother and wife's anguish."[32]
Falco starred as the title character, Nurse Jackie Peyton in the Showtimedark comedy series Nurse Jackie, which premiered on June 8, 2009, and ended on June 28, 2015. For the first season, she won her fourth Primetime Emmy Award, this time for Outstanding Lead Actress in a Comedy Series she also received nominations for four Golden Globe Awards and eight Screen Actors Guild Awards.[35][36][37] Alessandra Stanley of The New York Times wrote, "It's the compelling, enigmatic heroine who holds the errant pieces together. Jackie is not Carmela, but Ms. Falco brings some of Carmela’s prosaic manner and harsh certainty to the new role. Jackie has a very dry and mitigating sense of humor, but her righteous streak steers the story."[38]
It was announced in January 2013 that Falco would star in Liz Flahive's The Madrid off-Broadway. The limited engagement, directed by Leigh Silverman, began previews on February 5 with an official opening on February 26. Along with Falco, the play starred John Ellison, Christopher Evan Welch, Phoebe Strole, and Frances Sternhagen.[43] In 2016, Falco started portraying Sylvia Wittel on the Louis C.K. series Horace and Pete acting alongside C.K., Steve Buscemi, Alan Alda and Laurie Metcalf. The first episode was released on January 30, 2016, on C.K.'s website without any prior announcements.[44] New episodes premiered weekly until the tenth episode was released on April 2, 2016.[45] In the series Falco portrayed Horace and Sylvia's abused mother. James Poniewozik of The New York Times noted "Louis C. K. is reportedly submitting “Horace and Pete” for the Emmys as a drama. If it gets a nomination — Mr. Alda, Mr. Buscemi, Ms. Falco and Ms. Metcalf would all be strong picks".[46]
In 2020, she appeared as the lead character in the Paul AttanasioCBS police drama Tommy. Falco originally reprised her breakout role as Carmela Soprano for the 2021 film The Many Saints of Newark, a prequel to The Sopranos. However, her scenes were cut from the finished film.[52] Falco also starred in the FX true crime series Impeachment: American Crime Story (2021) portraying Hillary Rodham Clinton opposite Clive Owen's Bill Clinton and Beanie Feldstein's Monica Lewinsky. Ines Bellina of A.V. Club wrote, "Falco expertly guides us through a whole smorgasbord of human emotions. From rage to heartache to regret to shame to longing to pride to a pure, pure ache, we ride that emotional roller coaster firmly by her side".[53] In 2023 she played Amy Davidson, a fictional version of Pete Davidson's mother, in his semi-autobiographical series, Bupkis on Peacock. It was announced in May 2024 that the series had ended after its first season.[54]
She is a vegan and has worked with PETA on projects, including a public-service message urging parents to keep their children away from the circus.[59] She told Parade magazine, "I believe this is at the base of everything bad in society—you can bring it back to cruelty to animals. If you don't have respect for the life of any kind, it will manifest in more obvious ways."[60]
During the 2004 U.S. presidential election, Falco appeared in a 30-second television commercial on behalf of Mothers Opposing Bush in which she said, "Mothers always put their children first. Mr. Bush, can you say the same?" [61] Falco has become the spokesperson for Health Care for America Now and appeared on CNN on June 25, 2009.[62]
Health issues
Falco has struggled with alcoholism and decided to become sober in the early 1990s after "one particular night of debauchery." She said in an interview that it was difficult to be around the hard-partying cast of The Sopranos, stating, "This cast, in particular, they really love to hang out and party. They make it look like fun. And it was fun for me! They spend a lot more time without me than with me, by my own choice. I'm always invited, and I'm always there for two minutes and I leave, because I can't live in that world anymore. It's too dangerous."[63] She is an advocate of Alcoholics Anonymous' 12-step program.[64]
In 2003, Falco was diagnosed with breast cancer. She chose not to make the news public until the following year.[63]