Ozoralizumab

Ozoralizumab
Monoclonal antibody
Type	Whole antibody
Source	Humanized
Clinical data
Trade names	Nanozora
ATC code	none
Legal status
Legal status	Rx in Japan
Identifiers
CAS Number	1167985-17-2^Y
ChemSpider	none
UNII	05ZCK72TXZ
KEGG	D09944
Chemical and physical data
Formula	C₁₆₈₂H₂₆₀₈N₄₇₂O₅₃₈S₁₂
Molar mass	38434.85 g·mol⁻¹
^NY (what is this?) (verify)

Ozoralizumab (trade name Nanozora) is a trivalent anti-tumour necrosis factor alpha (TNFα) nanobody designed for the treatment of inflammatory diseases.^[1]

Ozoralizumab was developed by Pfizer Inc, and now belongs to Ablynx NV. Ablynx has licensed the rights to the antibody in China to Eddingpharm. In 2022, ozoralizumab was approved in Japan for the treatment of rheumatoid arthritis.^[2]

References

^ Kratz F, Elsadek B (July 2012). "Clinical impact of serum proteins on drug delivery". J Control Release. 161 (2): 429–45. doi:10.1016/j.jconrel.2011.11.028. PMID 22155554.
^ "Notification of Approval to Manufacture and Market Nanozora® 30mg Syringes for S.C. Injection, a Therapy for Rheumatoid Arthritis, in Japan Japan's First NANOBODY® Therapeutic" (Press release). Taisho Pharmaceutical Holdings. September 26, 2022.

Monoclonal antibodies for the immune system

Immune system

Human	Immunosuppression: Abrilumab Adalimumab^# Anifrolumab Atorolimumab Avelumab Avdoralimab Belimumab Bleselumab Brodalumab Camidanlumab tesirine Carlumab Cemiplimab Dupilumab Eldelumab Emapalumab Fresolimumab Golimumab Ianalumab^† Lanadelumab Lenzilumab Lerdelimumab Lirentelimab Lirilumab Mavrilimumab Metelimumab Morolimumab Namilumab Oleclumab Oxelumab§ Pamrevlumab Placulumab Relatlimab^† Sarilumab Sifalimumab Tabalumab Tezepelumab Ulocuplumab Varlilumab Immune activation: Ipilimumab Durvalumab Nivolumab Tremelimumab Urelumab Other: Bertilimumab Ontamalimab Zanolimumab Combination: Nivolumab/relatlimab
Mouse	Afelimomab Elsilimomab Faralimomab Gavilimomab Inolimomab Maslimomab Nerelimomab Odulimomab Telimomab aritox Vepalimomab Zolimomab aritox
Chimeric	Andecaliximab^† Basiliximab Clenoliximab Galiximab Gomiliximab Infliximab Keliximab Lumiliximab Priliximab Teneliximab Vapaliximab
Humanized	Immunosuppressive: Apolizumab^§ Aselizumab Atezolizumab Benralizumab Camrelizumab^† Cedelizumab Certolizumab pegol Crizanlizumab Daclizumab Eculizumab Efalizumab^‡ Epratuzumab Erlizumab Etrolizumab^† Fontolizumab Frexalimab^† Inebilizumab Itolizumab Lampalizumab^† Letolizumab Ligelizumab^† Lulizumab pegol Mepolizumab Mogamulizumab Natalizumab Ocrelizumab (+hyaluronidase) Omalizumab Ozoralizumab Pascolizumab Pateclizumab Pembrolizumab Pexelizumab Pidilizumab Plozalizumab PRO 140^† Quilizumab Ravulizumab Reslizumab Retifanlimab Rontalizumab Rovelizumab Ruplizumab Samalizumab Satralizumab Siplizumab Spartalizumab^† Talizumab Teclistamab Teplizumab Tislelizumab Tocilizumab Toralizumab Tregalizumab Vatelizumab Vedolizumab Visilizumab Vobarilizumab TGN1412^§ Immune activation: Dostarlimab Other: Ibalizumab
Chimeric + humanized	Otelixizumab Rozanolixizumab Sutimlimab

Interleukin

Human	Bermekimab Brazikumab Briakinumab Canakinumab Fezakinumab Fletikumab Guselkumab Secukinumab Sirukumab Tralokinumab Ustekinumab
Humanized	Anrukinzumab Bimekizumab Clazakizumab Gevokizumab Ixekizumab Mirikizumab^† Lebrikizumab Olokizumab^† Perakizumab Risankizumab Spesolimab Tildrakizumab
Veterinary	Lokivetmab

Inflammatory lesions

Mouse	Besilesomab Fanolesomab^‡ Lemalesomab Sulesomab

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

This monoclonal antibody–related article is a stub. You can help Wikipedia by expanding it.

This antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by expanding it.

Read other articles:

خوليو كويفا

هذه المقالة يتيمة إذ تصل إليها مقالات أخرى قليلة جدًا. فضلًا، ساعد بإضافة وصلة إليها في مقالات متعلقة بها. (يونيو 2019) خوليو كويفا معلومات شخصية الميلاد 12 أبريل 1897[1] ترينداد (كوبا) الوفاة 25 ديسمبر 1975 (78 سنة) هافانا مواطنة كوبا الحياة العملية المهنة قائد فر�...

Зомманж

ЗомманжZommange Країна Франція Регіон Гранд-Ест Департамент Мозель Округ Саррбур-Шато-Сален Кантон Дьєз Код INSEE 57763 Поштові індекси 57260 Координати 48°49′30″ пн. ш. 6°48′20″ сх. д.H G O Висота 210 - 242 м.н.р.м. Площа 6,34 км² Населення 47 (01-2020[1]) Густота 5,52 ос./км² �...

Amber

Amber kan verwijzen naar: Amber (potvis), een afvalproduct uit de darmen van potvissen Amber (parfum), een geurfamilie in parfums Het Engelse (en als ambre het Franse) woord voor barnsteen Amber (kleur), de oranje-gele kleur van barnsteen Amber (voornaam), een voornaam Amber, pseudoniem van Henna Goudzand Nahar Amber (artiest), een Nederlandse house/dance-act Amber (duo), een Nederlands close harmony-duo Amber Bondin, een Maltees zangeres Amber (deelauto), een Nederlandse zakelijke deelautodi...

Radu Nunweiller

Romanian footballer and manager Radu Nunweiller Nunweiller in 1970Personal informationFull name Radu NunweillerDate of birth (1944-11-16) 16 November 1944 (age 79)Place of birth Bucharest, RomaniaHeight 1.80 m (5 ft 11 in)Position(s) MidfielderYouth career1957–1962 Tânarul DinamovistSenior career*Years Team Apps (Gls)1962–1963 Viitorul București 1 (0)1963–1976 Dinamo București 295 (38)1976–1979 Corvinul Hunedoara 37 (2)Total 333 (40)International career1966–19...

Adolf Luther

Adolf Luther fotografiert von Lothar Wolleh Adolf Luther: Linsenallee (1990). Krefeld, Ostwall51° 19′ 54″ N, 6° 34′ 0″ O51.3316666666676.5666666666667 Adolf Luther (* 25. April 1912 in Uerdingen; † 20. September 1990 in Krefeld) war ein deutscher Jurist, Künstler und Bildhauer. Er war ein Hauptvertreter der kinetischen Kunst und Optical Art. Inhaltsverzeichnis 1 Leben 2 Literatur 3 Weblinks 4 Einzelnachweise Leben Luther studierte ab 1938 Rechtswisse...

Lætitia Sadier

French singer Lætitia SadierSadier in 2021Background informationBorn (1968-05-06) 6 May 1968 (age 55)Vincennes, FranceGenresPost-rock, indie rock, dream popInstrument(s)Vocals, synthesizers, guitar, keyboards, percussionYears active1987–presentMember ofStereolabFormerly ofMonadeMcCarthyMusical artist Lætitia Sadier (born 6 May 1968), sometimes known as Seaya Sadier, is a French musician best known as a founding member of the London-based avant-pop band Stereolab. In 1996, while Stere...

How Green Was My Valley (film)

1941 film by John Ford How Green Was My ValleyTheatrical release posterDirected byJohn FordScreenplay byPhilip DunneBased onHow Green Was My Valley 1939 novelby Richard LlewellynProduced byDarryl F. ZanuckStarring Walter Pidgeon Maureen O'Hara Donald Crisp Anna Lee Roddy McDowall Narrated byIrving PichelCinematographyArthur C. MillerEdited byJames B. ClarkMusic byAlfred NewmanDistributed byTwentieth Century-Fox Film CorporationRelease date October 28, 1941 (1941-10-28) Running ...

سنيكما

سنيكماسنيكما Snecma S.Aالشعارمعلومات عامةالجنسية فرنسيةالتأسيس (1945)النوع شركة تابعةالشكل القانوني شركة بأسهم مبسطة[1] المقر الرئيسي كوركورون، فرنساحلت محل Société européenne de propulsion (en) موقع الويب safran-aircraft-engines.com المنظومة الاقتصاديةالشركة الأم سافرانالصناعة aircraft and space construction (en...

Château-Larcher

Pour les articles homonymes, voir Château (homonymie) et Larcher. Château-Larcher L'église. Administration Pays France Région Nouvelle-Aquitaine Département Vienne Arrondissement Poitiers Intercommunalité Communauté de communes des Vallées du Clain Maire Mandat Francis Gargouil 2020-2026 Code postal 86370 Code commune 86065 Démographie Populationmunicipale 1 048 hab. (2020 ) Densité 68 hab./km2 Géographie Coordonnées 46° 25′ 06″ nord, 0° 18...

Troll gas field

Troll fieldTroll A platform in the Troll gas fieldLocation of Troll fieldCountryNorwayRegionNorth SeaLocationNorth SeaBlocks31/2, 31/3, 31/5, 31/6Offshore/onshoreoffshoreCoordinates60°38′44″N 3°43′35″E / 60.645556°N 3.726389°E / 60.645556; 3.726389OperatorEquinorPartnersEquinor, Petoro, Shell, ConocoPhillips, TotalEnergiesField historyDiscovery1979Start of production1995 Troll B platform Troll is a natural gas and oil field in the Norwegian sector of the No...

Catedral de la Santa Transfiguración del Salvador

Catedral de la Santa Transfiguración del Salvador LocalizaciónPaís ChipreDivisión LárnacaDirección Lárnaca (Chipre)Coordenadas 34°55′19″N 33°37′26″E / 34.92185, 33.62377Información religiosaCulto Iglesia ortodoxa chipriotaDiócesis Metrópolis de Kition y Exarcado de Lárnaca y LefkaraAdvocación Transfiguración del SalvadorDatos arquitectónicosTipo CatedralEstilo Bizantino[editar datos en Wikidata] La Catedral de la Santa Transfiguración del Sal...

Cha Cha Sing

2012 single by Berryz KoboCha Cha SingRegular Edition coverSingle by Berryz Kobofrom the album Berryz Mansion 9kai ReleasedJuly 25, 2012 (2012-07-25) (Japan)Genre J-pop EDM LabelPiccolo TownProducer(s)TsunkuBerryz Kobo singles chronology Be Genki (Naseba Naru!) (2012) Cha Cha Sing (2012) Want! (2012) Berryz Kobo×Cute singles chronology Chō Happy Song(2012) Music videosCha Cha Sing on YouTubeLoving You Too Much on YouTubeMomochi! Yurushite-nyan Taisō on YouTubeCha Cha Sin...

Icahn Enterprises L.P.

Artikel ini sebatang kara, artinya tidak ada artikel lain yang memiliki pranala balik ke halaman ini.Bantulah menambah pranala ke artikel ini dari artikel yang berhubungan atau coba peralatan pencari pranala.Tag ini diberikan pada April 2016. Icahn Enterprises L.P.Jenispublik (NYSE: IEP)Industriinvestasi, otomotif, permainan, tram, pengemasan produk, metal, real estate, dan produk hiasan rumahKantorpusatNew York City, New York, Amerika SerikatWilayah operasiSeluruh duniaTokohkunciKeith Cozza(...

Botschafter der Vereinigten Staaten

Flagge eines Botschafters der Vereinigten Staaten Die Botschafter der Vereinigten Staaten (US-Botschafter) sind Mitarbeiter der US-Regierung. Inhaltsverzeichnis 1 Ernennung und Entlassung 2 Akkreditierung 3 Abberufung 4 Liste von Botschaftern der Vereinigten Staaten nach Empfangsstaat 5 Liste von Ständigen Vertretern der Vereinigten Staaten nach internationaler Organisation 6 Bekannte US-Botschafter 7 Einzelnachweise Ernennung und Entlassung Die Botschafter werden vom jeweiligen US-Präsiden...

Bryant Johnson

American football player (born 1981) For the American handball player, see Bryant Johnson (handballer). American football player Bryant JohnsonJohnson with the San Francisco 49ersNo. 83, 80, 82, 89Position:Wide receiverPersonal informationBorn: (1981-03-07) March 7, 1981 (age 42)Baltimore, Maryland, U.S.Height:6 ft 3 in (1.91 m)Weight:212 lb (96 kg)Career informationHigh school:Baltimore City College(Baltimore, Maryland)College:Penn StateNFL Draft:2003 / Rou...

Battle of Cochin

This article includes a list of references, related reading, or external links, but its sources remain unclear because it lacks inline citations. Please help to improve this article by introducing more precise citations. (November 2023) (Learn how and when to remove this template message)Battle of CochinPart of Portuguese battles in the Indian OceanDuarte Pacheco's victory at the Battle of Cochin, Portuguese lithograph from 1840Date16 March – 3 July 1504LocationKochi, IndiaResult Decisive K...

Feng Shui 2

For the other uses, see Feng shui. 2014 Filipino filmFeng Shui 2Theatrical release posterDirected byChito S. RoñoScreenplay byRoy IglesiasChito S. RoñoStory byChito S. RoñoProduced by Charo Santos-Concio Malou N. Santos Kristina Bernadette C. Aquino StarringKris AquinoCoco MartinCinematographyNeil DazaEdited byCarlo Francisco ManatadMusic byCarmina CuyaProductioncompaniesABS-CBN Film Productions, Inc.K ProductionsDistributed byStar CinemaRelease date December 25, 2014 (2014-...

Angat Dam

Dam in Bulacan, PhilippinesAngat DamView of Angat Dam from San Lorenzo (Hilltop), Norzagaray, Bulacan.Location of Angat Dam in BulacanShow map of BulacanAngat Dam (Luzon)Show map of LuzonAngat Dam (Philippines)Show map of PhilippinesOfficial nameAngat Hydroelectic DamLocationBarangay San Lorenzo, Norzagaray, Bulacan, PhilippinesCoordinates14°52′15″N 121°08′30″E / 14.87083°N 121.14167°E / 14.87083; 121.14167Construction beganNovember 1961Opening da...

Long Stanton railway station

Former railway station in Cambridgeshire, England Long Stanton station building, with a bus travelling on the guided busway, October 2019 Long Stanton railway station was a station on the Great Eastern Railway, between Cambridge and Huntingdon. It served the villages of Longstanton and Willingham (being roughly midway between them), until closure in October 1970.[1] The station was immortalised in 1964 in the song Slow Train by Flanders and Swann. The railway line through Long Stanton...

Silando, Muara, Tapanuli Utara

SilandoDesaKantor Kepala Desa SilandoNegara IndonesiaProvinsiSumatera UtaraKabupatenTapanuli UtaraKecamatanMuaraKode pos22476Kode Kemendagri12.02.15.2008 Luas... km²Jumlah penduduk... jiwaKepadatan... jiwa/km² Silando adalah salah satu desa yang berada di Kecamatan Muara, Kabupaten Tapanuli Utara, Provinsi Sumatera Utara, Indonesia. Galeri Gereja HKBP Mual Nauli Silando Gereja HKI Silando lbsKecamatan Muara, Kabupaten Tapanuli Utara, Sumatera UtaraDesa Aritonang Bariba Niaek Batu Binum...

Strategi Solo vs Squad di Free Fire: Cara Menang Mudah!