NNC-711

NNC-711

Names
Preferred IUPAC name 1-(2-{[(Diphenylmethylidene)amino]oxy}ethyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid
Other names NO-711
Identifiers
CAS Number	159094-94-7^Y
3D model (JSmol)	Interactive image
ChemSpider	4358
PubChem CID	4515 123738 (HCl)
UNII	BGU9MZ2G30^Y
CompTox Dashboard (EPA)	DTXSID30166582
InChI InChI=1S/C21H22N2O3/c24-21(25)19-12-7-13-23(16-19)14-15-26-22-20(17-8-3-1-4-9-17)18-10-5-2-6-11-18/h1-6,8-12H,7,13-16H2,(H,24,25) Key: NGNALWDRPKNJGR-UHFFFAOYSA-N
SMILES C1CN(CC(=C1)C(=O)O)CCON=C(C2=CC=CC=C2)C3=CC=CC=C3
Properties
Chemical formula	C21H22N2O3
Molar mass	350.418 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

NNC-711 is an anticonvulsant, acting as a gamma-aminobutyric acid uptake inhibitor via inhibition of GAT-1.^[1]

References

1. Borden, L. A.; Murali Dhar, T. G.; Smith, K. E.; Weinshank, R. L.; Branchek, T. A.; Gluchowski, C (1994). "Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1". European Journal of Pharmacology. 269 (2): 219–24. doi:10.1016/0922-4106(94)90089-2. PMID 7851497.