Maltose O-acetyltransferase

maltose O-acetyltransferase
Identifiers
EC no.	2.3.1.79
CAS no.	81295-47-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a maltose O-acetyltransferase (EC 2.3.1.79) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + maltose ${\displaystyle \rightleftharpoons }$ CoA + 6-O-acetyl-alpha-D-glucopyranosyl-(1->4)-D-glucose

Thus, the two substrates of this enzyme are acetyl-CoA and maltose, whereas its two products are CoA and [[6-O-acetyl-alpha-D-glucopyranosyl-(1->4)-D-glucose]].

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:maltose O-acetyltransferase. Other names in common use include maltose transacetylase, maltose O-acetyltransferase, and MAT.

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1OCX, 2IC7, and 2P2O.

References

• Freundlieb S, Boos W (January 1982). "Maltose transacetylase of Escherichia coli: a preliminary report". Ann. Microbiol. 133A (1). Paris: 181–9. PMID 7041741.
• Brand B, Boos W (1991). "Maltose transacetylase of Escherichia coli. Mapping and cloning of its structural, gene, mac, and characterization of the enzyme as a dimer of identical polypeptides with a molecular weight of 20,000". J. Biol. Chem. 266 (21): 14113–8. doi:10.1016/S0021-9258(18)92816-4. PMID 1856235.
• Lo Leggio L, Dal Degan F, Poulsen P, Andersen SM, Larsen S (2003). "The structure and specificity of Escherichia coli maltose acetyltransferase give new insight into the LacA family of acyltransferases". Biochemistry. 42 (18): 5225–35. doi:10.1021/bi0271446. PMID 12731863.