Iodophenol O-methyltransferase

iodophenol O-methyltransferase
Identifiers
EC no.	2.1.1.26
CAS no.	37256-95-4
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, an iodophenol O-methyltransferase (EC 2.1.1.26) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + 2-iodophenol ${\displaystyle \rightleftharpoons }$ S-adenosyl-L-homocysteine + 2-iodophenol methyl ether

Thus, the two substrates of this enzyme are S-adenosyl methionine and 2-iodophenol, whereas its two products are S-adenosylhomocysteine and 2-iodophenol methyl ether.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:2-iodophenol O-methyltransferase.

References

• Tomita K, Cha CJ, Lardy HA (1964). "Enzymic O-methylation of iodinated phenols and thyroid hormones". J. Biol. Chem. 239: 1202–1207. PMID 14165927.