Hepatitis C virus stem-loop VII

Hepatitis C virus stem-loop VII
Predicted secondary structure and sequence conservation of HCV_SLVII
Identifiers
Symbol	HCV_SLVII
Rfam	RF00468
Other data
RNA type	Cis-reg
Domain(s)	Viruses
SO	SO:0000233
PDB structures	PDBe

Hepatitis C virus stem-loop VII is a regulatory element found in the coding region of the RNA-dependent RNA polymerase gene, NS5B. Similarly to stem-loop IV, the stem-loop structure is important (but not essential) for colony formation, though its exact function and mechanism are unknown.^[1]

See also

• Hepatitis C alternative reading frame stem-loop
• Hepatitis C virus (HCV) cis-acting replication element (CRE)
• Hepatitis C virus 3'X element

References

1. Lee H, Shin H, Wimmer E, Paul AV (October 2004). "cis-acting RNA signals in the NS5B C-terminal coding sequence of the hepatitis C virus genome". Journal of Virology. 78 (20): 10865–10877. doi:10.1128/JVI.78.20.10865-10877.2004. PMC 521798. PMID 15452207.

External links

• Page for Hepatitis C virus stem-loop VII at Rfam