Guanine-transporting ATPase

guanine-transporting ATPase
Identifiers
EC no.	3.6.3.37
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a guanine-transporting ATPase (EC 3.6.3.37) is an enzyme that catalyzes the chemical reaction

ATP + H₂O + guanineout ${\displaystyle \rightleftharpoons }$ ADP + phosphate + guaninein

The 3 substrates of this enzyme are ATP, H₂O, and guanine, whereas its 3 products are ADP, phosphate, and guanine. This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (guanine-importing).

References

• Dreesen TD, Johnson DH, Henikoff S (1988). "The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes". Mol. Cell. Biol. 8 (12): 5206–15. doi:10.1128/mcb.8.12.5206-5215.1988. PMC 365623. PMID 3149712.
• Tearle RG, Belote JM, McKeown M, Baker BS, Howells AJ (1989). "Cloning and characterization of the scarlet gene of Drosophila melanogaster". Genetics. 122 (3): 595–606. doi:10.1093/genetics/122.3.595. PMC 1203733. PMID 2503416.
• Griffiths JK, Sansom CE. "The Transporter Factsbook, Academic Press, San Diego, 1998". {{cite journal}}: Cite journal requires |journal= (help)