Guaifenesin/codeine

Guaifenesin/codeine

Combination of
Guaifenesin	Expectorant
Codeine	Antitussive
Clinical data
AHFS/Drugs.com	Monograph Multum Consumer Information
License data	US DailyMed: Guaifenesin codeine
Routes of administration	By mouth
ATC code	R05FA02 (WHO)
Legal status
Legal status	US: Schedule V[1][2]
Identifiers
KEGG	D02263

Guaifenesin/codeine is a fixed-dose combination cold medicine used for the treatment of cough.^[1] It contains guaifenesin, an expectorant; and codeine, as the phosphate, an opioid antitussive.^[1] It is taken by mouth.^[1]

It was approved for medical use in the United States in 2006.^[1] In 2022, it was the 272nd most commonly prescribed medication in the United States, with more than 800,000 prescriptions.^[3][4]

Society and culture

Brand names

Guaifenesin/codeine is available under multiple brand names including Allfen CD, Antituss AC, Bitex, Bron-Tuss, Brontex, Cheracol with Codeine, Cheratussin, Cheratussin AC, Codafen, Codar GF, Coditussin AC, Dex-Tuss, Diabetic Tussin C, Duraganidin NR, ExeClear-C, G Tussin AC, Gani-Tuss NR, Glydeine, Guaiatussin AC, Guaiatussin AC Sugar Free, Guaifen AC, Guaifenesin AC, Guiatuss AC, Guiatussin with Codeine, Halotussin AC, Iophen, Iophen-C NR, M-Clear, M-Clear WC, Mar-cof CG, Maxi-Tuss AC, Mytussin AC, Relcof C, Robafen AC, Robichem AC, Robitussin AC, Romilar AC, Tussi Organidin, Tussiden C, Tusso-C, Virtussin A/C, and Virtussin AC.^[5][6][7][8]

References

1. "Guaifenesin and codeine phosphate solution". DailyMed. 1 December 2019. Retrieved 19 January 2024.
2. "Over-the-Counter (OTC) Monograph M012: Cold, Cough, Allergy, Bronchodilator, and Antiasthmatic Drug Products for Over-the-Counter Human Use" (PDF). U.S. Food and Drug Administration (FDA). 14 October 2022. Retrieved 19 January 2024.
3. "The Top 300 of 2022". ClinCalc. Archived from the original on 30 August 2024. Retrieved 30 August 2024.
4. "Codeine; Guaifenesin Drug Usage Statistics, United States, 2013 - 2022". ClinCalc. Retrieved 30 August 2024.
5. "Guaifenesin and Codeine: Indications, Side Effects, Warnings". Drugs.com. 28 July 2023. Retrieved 19 January 2024.
6. "Codeine and guaifenesin Uses, Side Effects & Warnings". Drugs.com. 16 October 2023. Retrieved 19 January 2024.
7. "Guaifenesin: MedlinePlus Drug Information". MedlinePlus. Retrieved 19 January 2024.
8. "Codeine: MedlinePlus Drug Information". MedlinePlus. Retrieved 19 January 2024.