Fluprazine

Fluprazine

Clinical data
Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: uncontrolled
Identifiers
IUPAC name 2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethylurea
CAS Number	76716-60-4
PubChem CID	71153
ChemSpider	64297
UNII	713BBL6840
ChEMBL	ChEMBL2106753
CompTox Dashboard (EPA)	DTXSID70227545
Chemical and physical data
Formula	C14H19F3N4O
Molar mass	316.328 g·mol^−1
3D model (JSmol)	Interactive image
SMILES C1CN(CCN1CCNC(=O)N)C2=CC=CC(=C2)C(F)(F)F

Fluprazine (DU-27,716) is a drug of the phenylpiperazine class. It is a so-called serenic or antiaggressive agent.^[1] It is closely related to several other piperazines, including eltoprazine and batoprazine, and TFMPP, as well as more distantly to the azapirones such as buspirone. The pharmacology of fluprazine is unknown, but it is likely to act as an agonist at the 5-HT_1A and 5-HT_1B receptors like its sister compound eltoprazine.

See also

• Phenylpiperazine

References

1. van der Poel AM, Olivier B, Mos J, Kruk MR, Meelis W, van Aken JH (1982). "Anti-aggressive effect of a new phenylpiperazine compound (DU27716) on hypothalamically induced behavioural activities". Pharmacol Biochem Behav. 17 (1): 147–153. doi:10.1016/0091-3057(82)90277-5. PMID 6889746. S2CID 34142798.