Estradiol propoxyphenylpropionate

Estradiol propoxyphenylpropionate

Clinical data
Trade names	Durovex
Other names	EPPP; Estradiol 17-(4-propoxyphenyl)propanoate; Estradiol p-propoxyhydrocinnamate
Routes of administration	Intramuscular injection
Drug class	Estrogen; Estrogen ester
Identifiers
IUPAC name [(8R,9S,13S,14S,17S)-3-Hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl] 3-(4-propoxyphenyl)propanoate
CAS Number	7724-88-1
PubChem CID	90479312
ChemSpider	34995669
UNII	288OER048N
CompTox Dashboard (EPA)	DTXSID101046414
Chemical and physical data
Formula	C30H38O4
Molar mass	462.630 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CCCOc1ccc(CCC(=O)O[C@H]2CC[C@H]3[C@@H]4CCc5cc(O)ccc5[C@H]4CC[C@]23C)cc1
InChI InChI=1S/C30H38O4/c1-3-18-33-23-9-4-20(5-10-23)6-15-29(32)34-28-14-13-27-26-11-7-21-19-22(31)8-12-24(21)25(26)16-17-30(27,28)2/h4-5,8-10,12,19,25-28,31H,3,6-7,11,13-18H2,1-2H3/t25-,26-,27+,28+,30+/m1/s1 Key:JNWIUSBBFNMZRQ-BOJCFLQHSA-N

Estradiol propoxyphenylpropionate (EPPP), sold under the brand name Durovex, is an estrogen medication and estrogen ester which is no longer marketed.^[1] It is the C17β propoxyphenylpropionate (propoxyhydrocinnamate) ester of estradiol.^[1] It is a long-acting depot estrogen.^[2][3]

See also

• List of estrogen esters § Estradiol esters

References

1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 898. ISBN 978-1-4757-2085-3.
2. Baker AP, Bergman F, Paul KG (April 1967). "Studies of eosinophil granulocytes. 3. Steroid hormones and number of eosinophils in the uterus of the mouse and rat". Acta Endocrinologica. 54 (4): 696–706. doi:10.1530/acta.0.0560221. PMID 6071489.
3. Åkeson Å, Ehrenberg A (17 May 2014). Structure and Function of Oxidation–Reduction Enzymes: Proceedings of the Wenner-Gren Symposium Held at the Wenner-Gren Center, Stockholm, 23–27 August, 1970. Elsevier. pp. 216–. ISBN 978-1-4831-4755-0.