Enterovirus 5′ cloverleaf cis-acting replication element

Enterovirus 5′ cloverleaf cis-acting replication element
Predicted secondary structure and sequence conservation of Entero_5_CRE
Identifiers
Symbol	Entero_5_CRE
Rfam	RF00386
Other data
RNA type	Cis-reg
Domain(s)	Viruses
SO	SO:0000233
PDB structures	PDBe

The Enterovirus 5′ cloverleaf cis-acting replication element is an RNA element found in the 5′ UTR of Enterovirus genomes. The element has a cloverleaf like secondary structure and is known to be a multifunctional cis-acting replication element (CRE), required for the initiation of negative strand RNA synthesis.^[1]

See also

• Enteroviral 3′ UTR element
• Enterovirus cis-acting replication element

References

1. Barton DJ, O'Donnell BJ, Flanegan JB (March 2001). "5′ cloverleaf in poliovirus RNA is a cis-acting replication element required for negative-strand synthesis". The EMBO Journal. 20 (6): 1439–1448. doi:10.1093/emboj/20.6.1439. PMC 145522. PMID 11250909.

External links

• Page for Enterovirus 5′ cloverleaf cis-acting replication element at Rfam