Draft:Trans Ova Genetics

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Draft:Trans Ova Genetics
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Trans Ova Genetics
TypeSubsidiary
IndustryAnimal reproductive technology, Agricultural biotechnology
Founded1980
FounderDr. David Faber
HeadquartersSioux Center, Iowa, United States
Key people
Dr. David Faber (Founder), Dr. Kevin Hoogendoorn (CEO)
ProductsEmbryo transfer, IVF, sexed semen, cloning, genetic preservation
ParentURUS
Websitetransova.com

Trans Ova Genetics is an American animal reproductive technology company headquartered in Sioux Center, Iowa.[1] Founded in 1980 by veterinarian Dr. David Faber, the company provides assisted reproductive technologies for cattle, small ruminants, and swine, including embryo transfer, in vitro fertilization (IVF), sexed semen, genetic preservation, and cloning.[2] Trans Ova operates a network of regional and satellite centers across the United States and provides export services internationally.[3] In August 2022, the company was acquired by URUS, a holding company with cooperative and private ownership, for $170 million in upfront cash.[4]

History

Founding (1980)

Trans Ova Genetics was founded in 1980 by Dr. David Faber, a graduate of the University of Illinois College of Veterinary Medicine, in Sioux Center, Iowa.[5] Faber established the company initially as an extension of a large-animal veterinary practice, with a focus on on-farm embryo transfer services for beef and dairy cattle producers.[6] The company began without outside capital, with Faber developing its foundational techniques and equipment independently.[7]

Early growth and technology expansion

In its early years, Trans Ova transitioned from surgical to non-surgical embryo transfer procedures, a development Faber credited as the first of many technological advances at the company.[8] The company expanded its service offerings over subsequent decades to include in vitro fertilization, embryo splitting, sexed semen, and genetic preservation.[9] In 1998, Iowa's first transgenic bovine was born at Trans Ova's Genetics Advancement Center in Sioux Center.[10]

Trans Ova became involved in biomedical research through joint ventures, including Hematech, a company developing human antibodies using transgenic cattle, and Exemplar Genetics, which produced genetically engineered swine for use as biomedical research models.[11] In 2003, Discovery magazine ranked Trans Ova's transgenic calves, described as capable of producing human antibodies, among the top 100 scientific breakthroughs of 2002.[12]

Corporate ownership changes

Trans Ova Genetics was acquired by Intrexon Corporation, a synthetic biology company, in 2014.[13] The acquisition was documented in filings with the U.S. Securities and Exchange Commission (SEC).[14] Intrexon later rebranded as Precigen, Inc., a biopharmaceutical company, and Trans Ova operated as a non-healthcare subsidiary of Precigen.[15]

In July 2022, Precigen announced a definitive agreement to sell Trans Ova Genetics to URUS for $170 million in upfront cash and up to $10 million in earn-out consideration based on Trans Ova's performance in 2022 and 2023.[16] The transaction closed on August 18, 2022.[17] URUS, which includes dairy genetics brands such as Alta Genetics, ABS Global, and Sexing Technologies, added Trans Ova to its portfolio of cattle genetics and reproduction businesses.[18]

Leadership

Dr. David Faber served as founder and president of Trans Ova Genetics for more than four decades.[19] In 2024, the company announced the appointment of Dr. Kevin Hoogendoorn as Chief Executive Officer to lead the company's next phase of growth.[20]

Services

Trans Ova Genetics provides a range of assisted reproductive technologies (ART) for bovine (beef and dairy cattle), small ruminant (sheep and goats), and swine species.[21]

Embryo Transfer

Embryo transfer (ET) is the process by which embryos are collected from genetically superior donor animals and transferred to recipient cows for gestation.[22] Trans Ova offers embryo transfer services for both beef and dairy cattle producers, operating through regional centers, satellite locations, and on-farm programs.[23]

In Vitro Fertilization

Trans Ova offers bovine in vitro fertilization (IVF) services, in which oocytes (eggs) are collected from donor cows via ovum pick-up (OPU), fertilized in a laboratory, and cultured to the blastocyst stage before transfer to recipient cows.[24] The company has reported producing between 40% and 80% of elite Holstein bulls in the United States annually through its reproductive programs.[25]

Sexed Semen

Sexed semen technology allows producers to select the sex of resulting offspring with a high degree of accuracy.[26] Trans Ova offers sexed semen services for both beef and dairy cattle operations.[27]

Genetic Preservation and Cloning

Trans Ova provides genetic preservation services, including the cryopreservation of embryos and semen.[28] The company also provides animal cloning services for cattle, horses, small ruminants, and swine.[29] ViaGen, a subsidiary affiliated with Trans Ova's parent company URUS, specializes in companion animal and livestock cloning.[30]

Small Ruminant Services

Trans Ova offers reproductive services for sheep and goats including embryo transfer, IVF, and laparoscopic artificial insemination (LAI).[31]

International Export

The company provides genetics export services, enabling producers to ship embryos and semen internationally.[32] Trans Ova has established partnerships with organizations including Genetics Australia and expanded operations into Canada.[33]

Operations

Trans Ova Genetics operates through a network of regional centers, satellite centers, and on-farm technicians across the United States.[34] The company's main campus is located on a 120-acre facility north of Sioux Center, Iowa.[35]

The company has received federal research funding, as documented in its Small Business Innovation Research (SBIR) portfolio.[36] Trans Ova has been an exhibitor at industry events including the BIO International Convention[37] and World Dairy Expo.[38]

Trans Ova's operations have been noted for economic development impact in Iowa.[39]

Industry recognition and research

Trans Ova Genetics has been cited in national media coverage of the livestock genetics and cloning industries, including coverage of the cloning of a rare gaur in Wired (2001)[40] and coverage of the food cloning debate in Bloomberg Businessweek (2008).[41] Bloomberg News covered legal disputes in the dairy genetics market with reference to Trans Ova's industry in 2016[42] and 2018.[43] The Atlantic published a feature on the animal cloning industry in 2025 that included discussion of the company.[44]

Trans Ova has sponsored youth programs in livestock and agriculture, including 4-H and FFA competitions, and has awarded scholarships to students pursuing careers in animal reproduction, veterinary medicine, and biotechnology.[45] The company's Dr. David Faber Innovation Award recognizes contributions to the field of reproductive technology.[46]

Parent company: URUS

As of August 2022, Trans Ova Genetics operates as a subsidiary of URUS, a holding company that connects global agricultural genetics and reproduction businesses through a structure combining cooperative ownership and private investment.[47] Other URUS companies include ABS Global (bull semen), Alta Genetics, Acceligen (genomics), and Sexing Technologies (sexed semen).[48] The acquisition was financed through debt and was subject to clearance under the Hart-Scott-Rodino Antitrust Improvements Act of 1976.[49]

Notable technology milestones

1980 — Company founded; non-surgical embryo transfer developed in Sioux Center, Iowa.[50]

1998 — Iowa's first transgenic bovine born at Trans Ova's Genetics Advancement Center.[51]

2001 — Trans Ova's work on cloning of a gaur (a rare wild ox species) reported by Wired magazine.[52]

2002 — Discovery magazine ranked Trans Ova's transgenic calves among the world's top 100 scientific breakthroughs.[53]

2014 — Acquired by Intrexon Corporation (later Precigen).[54]

2022 — Acquired by URUS for $170 million in upfront cash on August 18, 2022.[55]

References

  1. ^ Faber, David. "Dr. David Faber, President, Trans Ova Genetics." SBN Online, 2012. https://sbnonline.com/article/dr-david-faber-president-trans-ova-genetics/
  2. ^ University of Illinois College of Veterinary Medicine. "Passion, Vision Put 1980 Graduate at the Forefront of Bovine Genetics." March 7, 2022. https://vetmed.illinois.edu/2022/03/07/passion-vision-put-1980-graduate-at-the-forefront-of-bovine-genetics/
  3. ^ Faber, David. "Dr. David Faber, President, Trans Ova Genetics." SBN Online, 2012. https://sbnonline.com/article/dr-david-faber-president-trans-ova-genetics/
  4. ^ PR Newswire / Precigen. "Precigen Completes Sale of Non-Healthcare Subsidiary Trans Ova Genetics." August 22, 2022. https://www.prnewswire.com/news-releases/precigen-completes-sale-of-non-healthcare-subsidiary-trans-ova-genetics-301609426.html
  5. ^ University of Illinois College of Veterinary Medicine. "Passion, Vision Put 1980 Graduate at the Forefront of Bovine Genetics." March 7, 2022. https://vetmed.illinois.edu/2022/03/07/passion-vision-put-1980-graduate-at-the-forefront-of-bovine-genetics/
  6. ^ Sioux City Journal. "Cloned Cows at Trans Ova Genetics Offer Hope for Fighting Human Diseases." https://siouxcityjournal.com/business/cloned-cows-at-trans-ova-genetics-offer-hope-for-fighting-human-diseases/article_e206c214-de9e-5a23-b88d-67a430f18a94.html
  7. ^ Faber, David. "Dr. David Faber, President, Trans Ova Genetics." SBN Online, 2012. https://sbnonline.com/article/dr-david-faber-president-trans-ova-genetics/
  8. ^ University of Illinois College of Veterinary Medicine. "Passion, Vision Put 1980 Graduate at the Forefront of Bovine Genetics." March 7, 2022. https://vetmed.illinois.edu/2022/03/07/passion-vision-put-1980-graduate-at-the-forefront-of-bovine-genetics/
  9. ^ Faber, David. "Dr. David Faber, President, Trans Ova Genetics." SBN Online, 2012. https://sbnonline.com/article/dr-david-faber-president-trans-ova-genetics/
  10. ^ Sioux City Journal. "Cloned Cows at Trans Ova Genetics Offer Hope for Fighting Human Diseases." https://siouxcityjournal.com/business/cloned-cows-at-trans-ova-genetics-offer-hope-for-fighting-human-diseases/article_e206c214-de9e-5a23-b88d-67a430f18a94.html
  11. ^ Sioux City Journal. "Cloned Cows at Trans Ova Genetics Offer Hope for Fighting Human Diseases." https://siouxcityjournal.com/business/cloned-cows-at-trans-ova-genetics-offer-hope-for-fighting-human-diseases/article_e206c214-de9e-5a23-b88d-67a430f18a94.html
  12. ^ Sioux City Journal. "Cloned Cows at Trans Ova Genetics Offer Hope for Fighting Human Diseases." https://siouxcityjournal.com/business/cloned-cows-at-trans-ova-genetics-offer-hope-for-fighting-human-diseases/article_e206c214-de9e-5a23-b88d-67a430f18a94.html
  13. ^ U.S. Securities and Exchange Commission. Exhibit 99.1, Intrexon Corporation acquisition filing, 2014. https://www.sec.gov/Archives/edgar/data/1356090/000119312514259968/d753890dex991.htm
  14. ^ U.S. Securities and Exchange Commission. Exhibit 99.1, Intrexon Corporation acquisition filing, 2014. https://www.sec.gov/Archives/edgar/data/1356090/000119312514259968/d753890dex991.htm
  15. ^ PR Newswire / Precigen. "Precigen Completes Sale of Non-Healthcare Subsidiary Trans Ova Genetics." August 22, 2022. https://www.prnewswire.com/news-releases/precigen-completes-sale-of-non-healthcare-subsidiary-trans-ova-genetics-301609426.html
  16. ^ Dairy Herd Network. "URUS to Purchase Trans Ova Genetics." 2022. https://www.dairyherd.com/news/business/urus-purchase-trans-ova-genetics
  17. ^ PR Newswire / Precigen. "Precigen Completes Sale of Non-Healthcare Subsidiary Trans Ova Genetics." August 22, 2022. https://www.prnewswire.com/news-releases/precigen-completes-sale-of-non-healthcare-subsidiary-trans-ova-genetics-301609426.html
  18. ^ Law Street Media. "URUS Will Acquire Precigen's Trans Ova Genetics for $170M." 2022. https://lawstreetmedia.com/deals/urus-will-acquire-precigens-trans-ova-genetics-for-170m
  19. ^ University of Illinois College of Veterinary Medicine. "Passion, Vision Put 1980 Graduate at the Forefront of Bovine Genetics." March 7, 2022. https://vetmed.illinois.edu/2022/03/07/passion-vision-put-1980-graduate-at-the-forefront-of-bovine-genetics/
  20. ^ Trans Ova Genetics. "About." https://transova.com/about
  21. ^ Faber, David. "Dr. David Faber, President, Trans Ova Genetics." SBN Online, 2012. https://sbnonline.com/article/dr-david-faber-president-trans-ova-genetics/
  22. ^ Drovers. "Embryo Transfer: Work Worth It for Cattle Producers?" https://www.drovers.com/news/beef-production/embryo-transfer-work-worth-it-cattle-producers
  23. ^ Faber, David. "Dr. David Faber, President, Trans Ova Genetics." SBN Online, 2012. https://sbnonline.com/article/dr-david-faber-president-trans-ova-genetics/
  24. ^ Trans Ova Genetics. "In Vitro Fertilization — Dairy." https://transova.com/service/dairy/in-vitro-fertilization
  25. ^ University of Illinois College of Veterinary Medicine. "Passion, Vision Put 1980 Graduate at the Forefront of Bovine Genetics." March 7, 2022. https://vetmed.illinois.edu/2022/03/07/passion-vision-put-1980-graduate-at-the-forefront-of-bovine-genetics/
  26. ^ Bloomberg News. "Battle Over $200-a-Vial Bull Semen Could Rock the Dairy Industry." January 26, 2016. https://www.bloomberg.com/news/articles/2016-01-26/battle-over-200-a-vial-bull-semen-could-rock-the-dairy-industry
  27. ^ Bloomberg News. "Sex Is Big Business in Dairy Farming and Focus of Legal Battles." January 3, 2018. https://www.bloomberg.com/news/articles/2018-01-03/sex-is-big-business-in-dairy-farming-and-focus-of-legal-battles
  28. ^ Trans Ova Genetics. "Cloning and Genetic Preservation Services." https://transova.com/service/cloning-services
  29. ^ The Atlantic. "The Animal Cloning Industry." July 2025. https://www.theatlantic.com/magazine/archive/2025/07/animal-cloning-industry/682892
  30. ^ The Atlantic. "The Animal Cloning Industry." July 2025. https://www.theatlantic.com/magazine/archive/2025/07/animal-cloning-industry/682892
  31. ^ Trans Ova Genetics. "Small Ruminant Services." https://transova.com/service/small-ruminant
  32. ^ Genetics Australia. "Media Release: Trans Ova Genetics Launching in Australia." https://genaust.com.au/news/media-release-trans-ova-genetics-launching-in-australia
  33. ^ Cowsmo. "Trans Ova Genetics Expands into Canada." https://cowsmo.com/news/trans-ova-genetics-expands-into-canada
  34. ^ Faber, David. "Dr. David Faber, President, Trans Ova Genetics." SBN Online, 2012. https://sbnonline.com/article/dr-david-faber-president-trans-ova-genetics/
  35. ^ Sioux City Journal. "Cloned Cows at Trans Ova Genetics Offer Hope for Fighting Human Diseases." https://siouxcityjournal.com/business/cloned-cows-at-trans-ova-genetics-offer-hope-for-fighting-human-diseases/article_e206c214-de9e-5a23-b88d-67a430f18a94.html
  36. ^ SBIR.gov. Trans Ova Genetics Company Portfolio. https://www.sbir.gov/portfolio/336927
  37. ^ BIO International Convention. Exhibitor Listing: Trans Ova Genetics Advanced Technologies Inc. https://convention.bio.org/exhibitors/trans-ova-genetics-advanced-technologies-inc
  38. ^ World Dairy Expo. Exhibitor Map, Booth 851. https://worlddairyexpo.com/pages/Exhibitor-Maps.php?booth_id=851&map_id=36
  39. ^ Iowa Legislature. Economic Development Report, Iowa Department. https://www.legis.iowa.gov/docs/publications/DF/12422.pdf
  40. ^ Wired. "Rare Cloned Ox Dies." January 2001. https://www.wired.com/2001/01/rare-cloned-ox-dies
  41. ^ Bloomberg Businessweek. "Uproar Over Cloned Food." January 15, 2008. https://www.bloomberg.com/news/articles/2008-01-15/uproar-over-cloned-food-copy-thatbusinessweek-business-news-stock-market-and-financial-advice
  42. ^ Bloomberg News. "Battle Over $200-a-Vial Bull Semen Could Rock the Dairy Industry." January 26, 2016. https://www.bloomberg.com/news/articles/2016-01-26/battle-over-200-a-vial-bull-semen-could-rock-the-dairy-industry
  43. ^ Bloomberg News. "Sex Is Big Business in Dairy Farming and Focus of Legal Battles." January 3, 2018. https://www.bloomberg.com/news/articles/2018-01-03/sex-is-big-business-in-dairy-farming-and-focus-of-legal-battles
  44. ^ The Atlantic. "The Animal Cloning Industry." July 2025. https://www.theatlantic.com/magazine/archive/2025/07/animal-cloning-industry/682892
  45. ^ Faber, David. "Dr. David Faber, President, Trans Ova Genetics." SBN Online, 2012. https://sbnonline.com/article/dr-david-faber-president-trans-ova-genetics/
  46. ^ Trans Ova Genetics. "Hong Wei Wins Dr. David Faber Innovation Award." March 2026. https://transova.com/2026/03/hong-wei-wins-dr-david-faber-innovation-award
  47. ^ PR Newswire / Precigen. "Precigen Completes Sale of Non-Healthcare Subsidiary Trans Ova Genetics." August 22, 2022. https://www.prnewswire.com/news-releases/precigen-completes-sale-of-non-healthcare-subsidiary-trans-ova-genetics-301609426.html
  48. ^ Law Street Media. "URUS Will Acquire Precigen's Trans Ova Genetics for $170M." 2022. https://lawstreetmedia.com/deals/urus-will-acquire-precigens-trans-ova-genetics-for-170m
  49. ^ U.S. Securities and Exchange Commission. Form 8-K, Precigen, Inc. Filed 2022. https://www.sec.gov/Archives/edgar/data/1356090/000095010322011927/dp176668_8k.htm
  50. ^ University of Illinois College of Veterinary Medicine. "Passion, Vision Put 1980 Graduate at the Forefront of Bovine Genetics." March 7, 2022. https://vetmed.illinois.edu/2022/03/07/passion-vision-put-1980-graduate-at-the-forefront-of-bovine-genetics/
  51. ^ Sioux City Journal. "Cloned Cows at Trans Ova Genetics Offer Hope for Fighting Human Diseases." https://siouxcityjournal.com/business/cloned-cows-at-trans-ova-genetics-offer-hope-for-fighting-human-diseases/article_e206c214-de9e-5a23-b88d-67a430f18a94.html
  52. ^ Wired. "Rare Cloned Ox Dies." January 2001. https://www.wired.com/2001/01/rare-cloned-ox-dies
  53. ^ Sioux City Journal. "Cloned Cows at Trans Ova Genetics Offer Hope for Fighting Human Diseases." https://siouxcityjournal.com/business/cloned-cows-at-trans-ova-genetics-offer-hope-for-fighting-human-diseases/article_e206c214-de9e-5a23-b88d-67a430f18a94.html
  54. ^ U.S. Securities and Exchange Commission. Exhibit 99.1, Intrexon Corporation acquisition filing, 2014. https://www.sec.gov/Archives/edgar/data/1356090/000119312514259968/d753890dex991.htm
  55. ^ PR Newswire / Precigen. "Precigen Completes Sale of Non-Healthcare Subsidiary Trans Ova Genetics." August 22, 2022. https://www.prnewswire.com/news-releases/precigen-completes-sale-of-non-healthcare-subsidiary-trans-ova-genetics-301609426.html

Categories Category:Biotechnology companies of the United States Category:Companies based in Iowa Category:In vitro fertilisation Category:1980 establishments in Iowa Category:Companies established in 1980

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