Dr. Samuel Guthrie House is a historic home located at Hounsfield in Jefferson County, New York. The home comprises a rectangular two-story, five-by-two-bay, brick Federal style core building and a rectangular one-story rear wing. The rear wing is in three sections: a section constructed around 1822, an addition from the early 20th century, and a third from about 1910.[2]
It was listed on the National Register of Historic Places in 1989.[1]
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