Dipeptidyl-peptidase III

Dipeptidyl-peptidase III
Identifiers
EC no.	3.4.14.4
CAS no.	77464-87-0
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Dipeptidyl-peptidase III (EC 3.4.14.4, dipeptidyl aminopeptidase III, dipeptidyl arylamidase III, enkephalinase B, red cell angiotensinase) is an enzyme.^[1][2] This enzyme catalyses the following chemical reaction

Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.

This cytosolic peptidase that is active at neutral pH.

References

1. McDonald JK (1998). "Dipeptidyl-peptidase III". In Barrett AJ, Rawlings NA, Woessner JG (eds.). Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. pp. 536–538.
2. Fukasawa K, Fukasawa KM, Iwamoto H, Hirose J, Harada M (June 1999). "The HELLGH motif of rat liver dipeptidyl peptidase III is involved in zinc coordination and the catalytic activity of the enzyme". Biochemistry. 38 (26): 8299–303. doi:10.1021/bi9904959. PMID 10387075.

External links

• Dipeptidyl-peptidase+III at the U.S. National Library of Medicine Medical Subject Headings (MeSH)