Diapolycopene oxygenase

Diapolycopene oxygenase
Identifiers
EC no.	1.14.99.44
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Diapolycopene oxygenase (EC 1.14.99.44, crtP) is an enzyme with systematic name 4,4'-diapolycopene,AH2:oxygen oxidoreductase (4,4'-hydroxylating).^[1][2] This enzyme catalyses the following chemical reaction

4,4'-diapolycopene + 4 AH₂ + 4 O₂ ${\displaystyle \rightleftharpoons }$ 4,4'-diapolycopenedial + 4 A + 6 H₂O

Diapolycopene oxygenase is involved in the biosynthesis of C30 carotenoids such as staphyloxanthin.

References

1. Mijts BN, Lee PC, Schmidt-Dannert C (April 2005). "Identification of a carotenoid oxygenase synthesizing acyclic xanthophylls: combinatorial biosynthesis and directed evolution". Chemistry & Biology. 12 (4): 453–60. doi:10.1016/j.chembiol.2005.02.010. PMID 15850982.
2. Tao L, Schenzle A, Odom JM, Cheng Q (June 2005). "Novel carotenoid oxidase involved in biosynthesis of 4,4'-diapolycopene dialdehyde". Applied and Environmental Microbiology. 71 (6): 3294–301. doi:10.1128/AEM.71.6.3294-3301.2005. PMC 1151855. PMID 15933032.

External links

• Diapolycopene+oxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)