Diadenosine hexaphosphate hydrolase (ATP-forming) (EC 3.6.1.61, Ndx1) is an enzyme with systematic name P1,P6-bis(5'-adenosyl)hexaphosphate nucleotidohydrolase (ATP-forming).[1] This enzyme catalyses the following chemical reaction
- (1) P1,P6-bis(5'-adenosyl)hexaphosphate + H2O 2 ATP
- (2) P1,P5-bis(5'-adenosyl)pentaphosphate + H2O ATP + ADP
- (3) P1,P4-bis(5'-adenosyl)tetraphosphate + H2O ATP + AMP
The enzyme requires the presence of the divalent cations (Mn2+, Mg2+, Zn2+, and Co2+).
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