Dehydro-L-gulonate decarboxylase

dehydro-L-gulonate decarboxylase
Identifiers
EC no.	4.1.1.34
CAS no.	9024-67-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The enzyme dehydro-L-gulonate decarboxylase (EC 4.1.1.34) catalyzes the chemical reaction

3-dehydro-L-gulonate ${\displaystyle \rightleftharpoons }$ L-xylulose + CO₂

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-dehydro-L-gulonate carboxy-lyase (L-xylulose-forming). This enzyme participates in pentose and glucuronate interconversions.

References

• Smiley JD, Ashwell G (1961). "Purification and properties of beta-L-hydroxy acid dehydrogenase II. Isolation of beta-keto-L-gluconic acid, an intermediate in L-xylulose biosynthesis". J. Biol. Chem. 236: 357–364.