Deacetyl-(citrate-(pro-3S)-lyase) S-acetyltransferase

deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase
Identifiers
EC no.	2.3.1.49
CAS no.	42616-18-2
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase (EC 2.3.1.49) is an enzyme that catalyzes the chemical reaction

S-acetylphosphopantetheine + deacetyl-[citrate-oxaloacetate-lyase((pro-3S)-CH₂COO-->acetate)] ${\displaystyle \rightleftharpoons }$ phosphopantetheine + [citrate-oxaloacetate-lyase((pro-3S)-CH₂COO-->acetate)]

Thus, the two substrates of this enzyme are S-acetylphosphopantetheine and [[deacetyl-[citrate-oxaloacetate-lyase((pro-3S)-CH2COO-->acetate)]]], whereas its two products are phosphopantetheine and [[citrate-oxaloacetate-lyase((pro-3S)-CH2COO-->acetate)]].

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is S-acetylphosphopantetheine:deacetyl-[citrate-oxaloacetate-lyase((pro -3S)-CH2COO-->acetate)] S-acetyltransferase. Other names in common use include S-acetyl phosphopantetheine:deacetyl citrate lyase, S-acetyltransferase, and deacetyl-[citrate-(pro-3S)-lyase] acetyltransferase.

References

• Singh M, Bottger B, Stewart C, Brooks GC, Srere PA (1973). "S-acetyl phosphopantetheine: deacetyl citrate lyase S-acetyl transferase from Klebsiella aerogenes". Biochem. Biophys. Res. Commun. 53 (1): 1–9. doi:10.1016/0006-291X(73)91392-2. PMID 4741546.