The product of this enzyme, D-alanyl-D-serine, can be incorporated into the peptidoglycan pentapeptide instead of the usual D-alanyl-D-alanine dipeptide.
References
^Dutka-Malen S, Molinas C, Arthur M, Courvalin P (March 1992). "Sequence of the vanC gene of Enterococcus gallinarum BM4174 encoding a D-alanine:D-alanine ligase-related protein necessary for vancomycin resistance". Gene. 112 (1): 53–8. doi:10.1016/0378-1119(92)90302-6. PMID1551598.
^Watanabe S, Kobayashi N, Quiñones D, Hayakawa S, Nagashima S, Uehara N, Watanabe N (March 2009). "Genetic diversity of the low-level vancomycin resistance gene vanC-2/vanC-3 and identification of a novel vanC subtype (vanC-4) in Enterococcus casseliflavus". Microbial Drug Resistance. 15 (1): 1–9. doi:10.1089/mdr.2009.0856. PMID19216682.