Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase

Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase
Identifiers
EC no.	2.4.1.254
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase (EC 2.4.1.254, BpUGT94B1, UDP-glucuronic acid:anthocyanin glucuronosyltransferase, UDP-glucuronic acid:anthocyanidin 3-glucoside 2'-O-beta-glucuronosyltransferase, BpUGAT, UDP-D-glucuronate:cyanidin-3-O-beta-glucoside 2-O-beta-glucuronosyltransferase) is an enzyme with systematic name UDP-D-glucuronate:cyanidin-3-O-beta-D-glucoside 2-O-beta-D-glucuronosyltransferase.^[1][2] This enzyme catalyses the following chemical reaction

UDP-D-glucuronate + cyanidin 3-O-beta-D-glucoside ${\displaystyle \rightleftharpoons }$ UDP + cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside

The enzyme is highly specific for cyanidin 3-O-glucosides and UDP-D-glucuronate.

References

1. Sawada S, Suzuki H, Ichimaida F, Yamaguchi MA, Iwashita T, Fukui Y, Hemmi H, Nishino T, Nakayama T (January 2005). "UDP-glucuronic acid:anthocyanin glucuronosyltransferase from red daisy (Bellis perennis) flowers. Enzymology and phylogenetics of a novel glucuronosyltransferase involved in flower pigment biosynthesis". The Journal of Biological Chemistry. 280 (2): 899–906. doi:10.1074/jbc.m410537200. PMID 15509561.
2. Osmani SA, Bak S, Imberty A, Olsen CE, Møller BL (November 2008). "Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses". Plant Physiology. 148 (3): 1295–308. doi:10.1104/pp.108.128256. PMC 2577238. PMID 18829982.

External links

• Cyanidin-3-O-glucoside+2-O-glucuronosyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)