Established on 26 Nov 1895 as an Eparchy (Diocese) of Minya (Curiate Italian Ermopoli Maggiore), the territory split off from the Apostolic Vicariate of Egypt.
Archbishop-bishop Isaac Ghattas (8 May 1967 – death 8 Jun 1977), previously Eparch (Bishop) of Luqsor of the Copts (Egypt) (21 Jun 1949 – 8 May 1967)
Antonios Naguib (26 Jul 1977 – 29 Sep 2002), later Patriarch of Alexandria of the Copts (Egypt) ([30 Mar 2006] 7 Apr 2006 – 15 Jan 2013), also President of Synod of the Catholic Coptic Church (7 Apr 2006 – 15 Jan 2013), President of Assembly of the Catholic Hierarchy of Egypt (7 Apr 2006 – 15 Jan 2013); created Cardinal-Patriarch (20 Nov 2010 – ...)
Ibrahim Isaac Sedrak (5 Oct 2002 – 15 Jan 2013), later Patriarch of Alexandria of the Copts (Egypt) ([15 Jan 2013] 18 Jan 2013 – ...), also President of Synod of the Catholic Coptic Church (15 Jan 2013 – ...), President of Assembly of the Catholic Hierarchy of Egypt (15 Jan 2013 – ...)
Botros Fahim Awad Hanna (8 Apr 2013 – 7 Oct 2020); previously Titular Bishop of Mareotes (6 Sep 2006 – 8 Apr 2013) & Bishop of Curia of the Copts ([31 Aug 2006] 6 Sep 2006 – 8 Apr 2013)