4-hydroxyphenylpyruvate decarboxylase

4-hydroxyphenylpyruvate decarboxylase
Identifiers
EC no.	4.1.1.80
CAS no.	109300-96-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The enzyme 4-hydroxyphenylpyruvate decarboxylase (EC 4.1.1.80) catalyzes the chemical reaction

4-hydroxyphenylpyruvate ${\displaystyle \rightleftharpoons }$ 4-hydroxyphenylacetaldehyde + CO₂

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 4-hydroxyphenylpyruvate carboxy-lyase (4-hydroxyphenylacetaldehyde-forming). This enzyme is also called 4-hydroxyphenylpyruvate carboxy-lyase.

References

• Rueffer M, Zenk MH (1987). "Distant precursors of benzylisoquinoline alkaloids and their enzymatic formation". Z. Naturforsch. C: Biosci. 42: 319–332.