3-oxoadipate enol-lactonase

3-oxoadipate enol-lactonase
3-Oxoadipate enol-lactonase homodimer, Paraburkholderia xenovorans
Identifiers
EC no.	3.1.1.24
CAS no.	9031-04-3
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

The enzyme 3-oxoadipate enol-lactonase (EC 3.1.1.24) catalyzes the reaction

3-oxoadipate enol-lactone + H₂O ${\displaystyle \rightleftharpoons }$ 3-oxoadipate

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is 4-carboxymethylbut-3-en-4-olide enol-lactonohydrolase. Other names in common use include carboxymethylbutenolide lactonase, β-ketoadipic enol-lactone hydrolase, 3-ketoadipate enol-lactonase, 3-oxoadipic enol-lactone hydrolase, and β-ketoadipate enol-lactone hydrolase. This enzyme participates in benzoate degradation via hydroxylation.

References

• Ornston LN (August 1966). "The conversion of catechol and protocatechuate to β-ketoadipate by Pseudomonas putida. II. Enzymes of the protocatechuate pathway". The Journal of Biological Chemistry. 241 (16): 3787–94. doi:10.1016/S0021-9258(18)99840-6. PMID 5916392.
• Ornston LN (1970). "Conversion of catechol and protocatechuate to β-ketoadipate (Pseudomonas putida)". Conversion of catechol and protocatechuate to β-ketoadipate (Pseudomonas putida). Methods Enzymol. Vol. 17A. pp. 529–549. doi:10.1016/0076-6879(71)17237-0. ISBN 978-0-12-181874-6.