3-dehydroshikimate dehydratase

3-dehydroshikimate dehydratase
Identifiers
EC no.	4.2.1.118
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

3-dehydroshikimate dehydratase (EC 4.2.1.118) is an enzyme with systematic name 3-dehydroshikimate hydro-lyase.^[1][2] This enzyme catalyses the following chemical reaction

3-dehydro-shikimate ${\displaystyle \rightleftharpoons }$ 3,4-dihydroxybenzoate + H₂O

This enzyme catalyses an early step in the biosynthesis of petrobactin.

References

1. Fox DT, Hotta K, Kim CY, Koppisch AT (November 2008). "The missing link in petrobactin biosynthesis: asbF encodes a (−)-3-dehydroshikimate dehydratase". Biochemistry. 47 (47): 12251–3. doi:10.1021/bi801876q. PMID 18975921.
2. Pfleger BF, Kim Y, Nusca TD, Maltseva N, Lee JY, Rath CM, Scaglione JB, Janes BK, Anderson EC, Bergman NH, Hanna PC, Joachimiak A, Sherman DH (November 2008). "Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis". Proceedings of the National Academy of Sciences of the United States of America. 105 (44): 17133–8. Bibcode:2008PNAS..10517133P. doi:10.1073/pnas.0808118105. PMC 2579390. PMID 18955706.

External links

• 3-dehydroshikimate+dehydratase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)